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Postdoc John Maciejowski wins 2016 Regeneron Prize for Creative Innovation

John Maciejowski, a postdoctoral fellow in Titia de Lange’s Laboratory of Cell Biology and Genetics, has received the 2016 Regeneron Prize for Creative Innovation. The award, given by Regeneron Pharmaceuticals, Inc., recognizes innovative young scientists based on proposals they submit that have ...

Researchers uncover how “silent” genetic changes drive cancer

At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make. Each word is read by a molecule known as a tRNA. “We’ve long thought of these molecules as little more than middle men participating in the process of translating proteins...

Researchers find new signs of stress damage in the brain, plus hope for prevention

Chronic stress can make us worn-out, anxious, depressed—in fact, it can change the architecture of the brain. New research at The Rockefeller University shows that when mice experience prolonged stress, structural changes occur within a little-studied region of their amygdala, a part of the brain...

35 labs and counting: How the Robertson Therapeutic Development Fund speeds translational research at Rockefeller

by Alexandra MacWade, assistant editor Developing a new medical product is a complex, high-risk endeavor. Of the thousands of clinically promising concepts scientists formulate each year, only a small fraction move beyond the lab. The Robertson TDF was created to advance work that has gone beyon...

Scientists find evidence that cancer can arise from changes in the proteins that package DNA

A mutation that affects the proteins that package DNA—without changing the DNA itself—can cause a rare form of cancer, according to new findings in this week’s Science from researchers at Rockefeller University. The mutation is present in histones, the protein scaffolding around which DNA w...

C. David Allis receives the 2016 Gruber Genetics Prize

C. David Allis, Joy and Jack Fishman Professor and head of the Laboratory of Chromatin Biology and Epigenetics, has won the 2016 Gruber Genetics Prize. He shares the $500,000 award with Michael Grunstein of the University of California, Los Angeles. The award, given by The Gruber Foundation, reco...

New method allows first look at key stage of human development, embryo implantation

Accompanying commentary recommends revisiting current bioethical guidelines in light of advance       Despite significant biomedical advances in recent decades, the very earliest events of human development­—those that occur during a critical window just after fertilization—h...

Charles Rice wins Belgium’s highest scientific prize

Charles M. Rice, Maurice R. and Corinne P. Greenberg Professor in Virology and head of the Laboratory of Virology and Infectious Disease, has been honored with the 2016 InBev-Baillet Latour Health Prize for his work on the hepatitis C virus. Queen Mathilde of Belgium presented Rice with the prize...

An experimental Alzheimer’s drug reverses genetic changes thought to spur the disease

Aging takes its toll on the brain, and the cells of the hippocampus—a brain region with circuitry crucial to learning and memory—are particularly vulnerable to changes that can lead to Alzheimer’s disease or cognitive decline. With the hope of counteracting the changes that can lead to these t...

In the News - The New Yorker - Allis

Same but Different: How epigenetics can blur the line between nature and nurture "Allis walked me to his lab, a fluorescent-lit space overlooking the East River, divided by wide, polished-stone benches. A mechanical stirrer, whirring in a corner, clinked on the edge of a glass beaker. 'Two featur...