New insights about gene regulation in liver cells could lead to better treatments for a common tumor type.

In the rats that roam New York City’s streets and tunnels, scientists have found a virus that resembles hepatitis C. They have used it to create the first animal model of the human disease, a breakthrough that potentially could yield a much-needed vaccine.

Scientists have identified several genetic mechanisms by which antibiotic resistance may have arisen in a bacterium that causes deadly infections.

Jeremy M. Rock uses genetics to investigate how the microbe causes disease. He will join Rockefeller’s faculty on January 1, 2018.

Searching for a way to thwart Zika, scientists have discovered an antibody with a potent ability to neutralize the virus.

The centromere region of chromosomes retains the same DNA from one generation to the next. Scientists have gained new insights into how it avoids being scrambled in normal cells, and how it becomes unstable in cancer.

Some viruses can insert their genetic material into the genome of their host, creating a genetic fossil record. Researchers have uncovered how our ancestors may have wiped out one such virus around 11 million years ago.

Researchers have found that the bacterial immune system targets an invading virus as soon as it enters the cell. This discovery answers a long-standing question about how microbes defend themselves.

There are more than 25 drugs to control HIV, yet the virus remains one of the world’s biggest health problems. One of the many challenges with existing therapies is that a dormant version of the virus is always lurking in the background, ready to attack the immune system as soon as treatment is i...

As much as we try to avoid it, ­we are constantly sharing germs with those around us. But even when two people have the same infection, the resulting illnesses can be dramatically different—mild for one person, severe or even life-threatening for the other. Now, new research from The Rockefell...