News & HighlightsNews
Study reveals the structure of a protein crucial for DNA replication
Our DNA contains instructions crucial for virtually all forms of life on this planet. But for life to propagate, this blueprint must be copied and passed on to future generations. New findings describing the structure of a key molecule involved in DNA replication place another piece in the puzzle...
MacKinnon lab charts the anatomy of three molecular channels
Using a state-of-the-art imaging technology in which molecules are deep frozen, scientists in Roderick MacKinnon’s lab at Rockefeller University have reconstructed in unprecedented detail the three-dimensional architecture of three channels that provide a path for specific types of ions to travel...
Biophysicist Gregory M. Alushin receives White House honor for early career scientists
Gregory M. Alushin, assistant professor and head of the Laboratory of Structural Biophysics and Mechanobiology, has been chosen by President Obama as one of 102 researchers to receive the Presidential Early Career Award for Scientists and Engineers, the highest honor given by the U.S. government ...
New molecular map reveals how cells spew out potassium
New research from Roderick MacKinnon's Laboratory of Molecular Neurobiology and Biophysics at The Rockefeller University has determined, for the first time, the complete structure of an ion channel that plays an important role in cellular electrical signaling by sending potassium ions out of the ...
Pels Family Center for Biochemistry and Structural Biology receives new $10 million grant
by Alexandra MacWade, assistant editor A new $10 million endowment gift made by the Donald A. Pels Charitable Trust will provide ongoing support for the university’s chemical and structural biologists through the Pels Family Center for Biochemistry and Structural Biology. Mr. Pels, who was a Roc...
New structure shows how cells assemble protein-making machinery
Scientists at The Rockefeller University have created the most detailed three-dimensional images to date of an important step in the process by which cells make the nano-machines responsible for producing all-important protein. The results, described December 15 in Science, are prompting the rese...
First structural map of the cystic fibrosis protein sheds light on how mutations cause disease
Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure. This achievement, described December 1 in Cell, offers the kinds of insights essential to better understanding and treating this oft...
Survey of New York City soil uncovers medicine-making microbes
Microbes have long been an invaluable source of new drugs. And to find more, we may have to look no further than the ground beneath our feet. Researchers at The Rockefeller University have shown that the dirt beneath New York City teems with our tiny allies in the fight against disease. In soil c...
Researchers discover new antibiotics by sifting through the human microbiome
Most antibiotics in use today are based on natural molecules produced by bacteria—and given the rise of antibiotic resistance, there’s an urgent need to find more of them. Yet coaxing bacteria to produce new antibiotics is a tricky proposition. Most bacteria won’t grow in the lab. And even whe...
Researchers shed new light on RNA’s journey out of a cell’s nucleus
Cells secure DNA within their nuclei like a secret code stashed in a vault. However, the tightly controlled borders of the nucleus create a challenge: In order for the cell to produce essential proteins, messages derived from DNA must somehow escape the nucleus in the form of RNA molecules. New w...
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