Spatially Resolved Single-cell Genomics and Functional Genomics
The Postdoctoral Researchers Sponsored Lecture
Event Details
- Type
- Friday Lecture Series
- Speaker(s)
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Xiaowei Zhuang, Ph.D., David B. Arnold Jr. Professor of Science, professor of chemistry and chemical biology, professor of physics, Harvard University; investigator, Howard Hughes Medical Institute
- Speaker bio(s)
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Xiaowei Zhuang is an investigator of the Howard Hughes Medical Institute (HHMI) and the David B. Arnold Professor of Science at Harvard University. She pioneered the development of super-resolution imaging and genome-scale imaging methods. She invented stochastic optical reconstruction microscopy (STORM), a super-resolution imaging method that broke the diffraction limit and allowed light microscopy with nanometer-scale resolution. Using STORM, she discovered novel molecular structures in cells. She invented a genome-scale imaging method, multiplexed error-robust fluorescence in situ hybridization (MERFISH), which enabled spatially resolved single-cell transcriptomics, 3D genomics, epigenomics, and functional genomics. Using MERFISH, she made discoveries in areas ranging from the molecular signatures, spatial organization, and functions of cells in complex tissues to the 3D genome organization and gene regulation in cells.
Zhuang received her undergraduate training from the University of Science and Technology of China, her Ph.D. degree under the supervision of Prof. Y. R. Shen from the University of California at Berkeley, and her postdoctoral training under the supervision of Prof. Steven Chu at Stanford University. She received honorary doctorate degrees from the Stockholm University, the Delft University of Technology, and the Icahn School of Medicine at Mount Sinai. Zhuang is a member of the National Academy of Sciences, National Academy of Medicine, and the American Academy of Arts and Sciences, a fellow of the National Academy of Inventors, a member of the American Philosophical Society, and a foreign associate of the Chinese Academy of Sciences and the European Molecular Biology Organization. Her awards include the Ernest Solvay Prize, National Inventors Hall of Fame, the Dreyfus Prize in Chemical Sciences, the Breakthrough Prize in Life Sciences, the Heinrich Wieland Prize, the Heineken Prize for Biochemistry and Biophysics, the Lurie Prize in Biomedical Sciences, the Vilcek Prize in Biomedical Science, the Pearl Meister Greengard Prize, the National Academy of Sciences Award for Scientific Discovery, the Raymond and Beverly Sackler International Prize in Biophysics, the Max Delbruck Prize in Biological Physics, the MacArthur Fellowship.
- Open to
- Tri-Institutional