Understanding the S. aureus A-toxin Interaction with ADAM10 to Mitigate Disease
Event Details
- Type
- Other Seminars
- Speaker(s)
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Juliane Bubeck-Wardenburg, M.D., Ph.D., professor, Washington University in St. Louis
- Speaker bio(s)
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Dr. Juliane Bubeck Wardenburg is the Donald B. Strominger Professor of Pediatrics and Chief of Pediatric Critical Care at Washington University. She received her M.D. and Ph.D. degrees in Immunology from Washington University in St. Louis, subsequently pursuing clinical training in General Pediatrics and Pediatric Critical Care at the University of Chicago. During this time, Julie investigated the pathogenesis of Staphylococcus aureus infection in the laboratory of Dr. Olaf Schneewind in the Department of Microbiology as a Pediatric Scientist Development Program Fellow. Since 2008, the Bubeck Wardenburg laboratory has focused on the role of bacterial toxins in perturbation of host cellular and tissue homeostasis. Julie is known internationally for her expertise in the molecular pathogenesis of Staphylococcus aureus disease. Her laboratory has made seminal contributions to understanding how S. aureus alpha-toxin contributes to infection, positioning this protein as a leading target of S. aureus vaccines in human clinical trials. As the founder of Forward Defense, LLC, she has advanced a novel approach to the development of a S. aureus vaccine designed for infants and children. As a practicing clinician, Julie has a deep understanding of the challenges of preventing and managing severe clinical infections. She is the recipient of the Society for Pediatric Research Young Investigator Award and the University of Chicago Distinguished Investigator Award. In 2012, she was named a Burroughs Wellcome Investigator in the Pathogenesis of Infectious Diseases. She has been elected to the American Society for Clinical Investigation and the American Academy of Physicians.
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- Tri-Institutional