Publications

Publications

2022

Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance. 

Wang Z, Koirala B, Hernandez Y, Zimmerman M, Brady SF.

Science. 2022 May 27;376(6596):991-996. doi: 10.1126/science.abn4213. Epub 2022 May 26. PMID: 35617397

The integrated stress response remodels the microtubule-organizing center to clear unfolded proteins following proteotoxic stress.

Hurwitz B, Guzzi N, Gola A, Fiore VF, Sendoel A, Nikolova M, Barrows D, Carroll TS, Pasolli HA, Fuchs E.

Elife. 2022 Jun 27;11:e77780. doi: 10.7554/eLife.77780. PMID: 35758650 Free PMC article.

Lymphatics act as a signaling hub to regulate intestinal stem cell activity.

Niec RE, Chu T, Schernthanner M, Gur-Cohen S, Hidalgo L, Pasolli HA, Luckett KA, Wang Z, Bhalla SR, Cambuli F, Kataru RP, Ganesh K, Mehrara BJ, Pe’er D, Fuchs E.

Cell Stem Cell. 2022 Jul 7;29(7):1067-1082.e18. doi: 10.1016/j.stem.2022.05.007. Epub 2022 Jun 20. PMID: 35728595

2021

Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories.

Gonzales KAU, Polak L, Matos I, Tierney MT, Gola A, Wong E, Infarinato NR, Nikolova M, Luo S, Liu S, Novak JSS, Lay K, Pasolli HA, Fuchs E.

Science. 2021 Nov 26;374(6571):eabh2444. doi: 10.1126/science.abh2444. Epub 2021 Nov 26. PMID: 34822296 Free PMC article.

Scanning electron microscopy of murine skin ultrathin sections and cultured keratinocytes.

Banerjee A, Biswas R, Lim R, Pasolli HA, Raghavan S.

STAR Protoc. 2021 Aug 17;2(3):100729. doi: 10.1016/j.xpro.2021.100729. eCollection 2021 Sep 17. PMID: 34458866 Free PMC article.

Uncovering potential interspecies signaling factors in plant-derived mixed microbial culture.

Domzalski A, Perez SD, Yoo B, Velasquez A, Vigo V, Pasolli HA, Oldham AL, Henderson DP, Kawamura A.

Bioorg Med Chem. 2021 Jul 15;42:116254. doi: 10.1016/j.bmc.2021.116254. Epub 2021 Jun 4. PMID: 34119697 Free PMC article.

2020

BMP signaling: at the gate between activated melanocyte stem cells and differentiation.

Infarinato NR, Stewart KS, Yang Y, Gomez NC, Pasolli HA, Hidalgo L, Polak L, Carroll TS, Fuchs E.

Genes Dev. 2020 Dec 1;34(23-24):1713-1734. doi: 10.1101/gad.340281.120. Epub 2020 Nov 12. PMID: 33184221 Free PMC article.

Mechanics of a multilayer epithelium instruct tumour architecture and function.

Fiore VF, Krajnc M, Quiroz FG, Levorse J, Pasolli HA, Shvartsman SY, Fuchs E.

Nature. 2020 Sep;585(7825):433-439. doi: 10.1038/s41586-020-2695-9. Epub 2020 Sep 2. PMID: 32879493 Free PMC article.

m6A RNA methylation impacts fate choices during skin morphogenesis.

Xi L, Carroll T, Matos I, Luo JD, Polak L, Pasolli HA, Jaffrey SR, Fuchs E.

Elife. 2020 Aug 26;9:e56980. doi: 10.7554/eLife.56980. PMID: 32845239 Free PMC article.

Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells.

Shwartz Y, Gonzalez-Celeiro M, Chen CL, Pasolli HA, Sheu SH, Fan SM, Shamsi F, Assaad S, Lin ET, Zhang B, Tsai PC, He M, Tseng YH, Lin SJ, Hsu YC.

Cell. 2020 Aug 6;182(3):578-593.e19. doi: 10.1016/j.cell.2020.06.031. Epub 2020 Jul 16. PMID: 32679029 Free PMC article.

Liquid-liquid phase separation drives skin barrier formation.

Quiroz FG, Fiore VF, Levorse J, Polak L, Wong E, Pasolli HA, Fuchs E.

Science. 2020 Mar 13;367(6483):eaax9554. doi: 10.1126/science.aax9554. PMID: 32165560 Free PMC article.