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St. Giles Laboratory of Human Genetics of Infectious Diseases

Jean-Laurent Casanova, M.D., Ph.D.

Levy Family Professor
Investigator, Howard Hughes Medical Institute
  • Genetics and Genomics
  • Immunology, Virology, and Microbiology
  • Mechanisms of Human Disease
  • Neurosciences and Behavior
  • Organismal Biology and Evolution
  • Stem Cells, Development, Regeneration, and Aging

News

The antioxidant glutathione discovered to play a key role in proper protein folding

April 17, 2026
The findings may lead to new therapeutic interventions for certain types of neurodegeneration and cancers.

Programming the immune system to manufacture its own therapeutic proteins

April 16, 2026
By editing blood stem cells, researchers show that the immune system itself can be transformed into a durable, boostable source of therapeutic proteins—opening the door to potential single-shot treatments for diseases ranging from HIV to cancer.

Novel tool could identify new therapeutic targets in complex diseases like cancer

April 15, 2026
Researchers devised a platform for mapping the regulatory nodes where genetic variations converge to drive changes in cell behavior.
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Upcoming Events

Innate Immune Programs Shaping Neurodegeneration

April 20, 2026
1:30 PM - 2:30 PM | ZUCKERMAN AUDITORIUM, MSKCC, 417 E. 68TH ST.

Noncanonical Roles of Hepatitis B virus Precore RNA in Reverse Transcription

April 21, 2026
2:00 PM - 3:15 PM | CARSON FAMILY AUDITORIUM (CRC)

Beyond Synapses: Reconfigurability as a Unifying Principle of Learning.

April 21, 2026
4:00 PM - 5:00 PM | CARSON FAMILY AUDITORIUM (CRC)
  • View all upcoming events
  • Laboratories 75/91
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Conflict of Interest in Research