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St. Giles Laboratory of Human Genetics of Infectious Diseases

Jean-Laurent Casanova, M.D., Ph.D.

Levy Family Professor
Investigator, Howard Hughes Medical Institute
  • Genetics and Genomics
  • Immunology, Virology, and Microbiology
  • Mechanisms of Human Disease
  • Neurosciences and Behavior
  • Organismal Biology and Evolution
  • Stem Cells, Development, Regeneration, and Aging

News

This epigenetic switch could be targeted by new cancer therapies

March 11, 2026
Researchers were able to shut down certain malignancies by disabling a protein complex that regulates cell differentiation.

This tiny cellular portal could open vast possibilities for medicine

March 9, 2026
Michael Rout has spent decades studying the molecular machinery that controls all traffic in and out of the cell’s nucleus. His research could lead to new treatments for cancer and viral diseases.

New tracking tool reveals how T cells adapt in different organs

March 5, 2026
Researchers uncovered immune dynamics that may inform future therapies for infection, cancer, and autoimmunity.
  • View all news

Upcoming Events

Understanding NIH's Policy for Making Articles Publicly Accessible

March 12, 2026
2:00 PM - 3:00 PM | WEBINAR

Stem Cell Clonality and the Niche

March 13, 2026
3:30 PM - 4:30 PM | CASPARY AUDITORIUM
The Bruce Merrifield Distinguished Lecture

Colorectal Cancers with Distinct Metastatic Potential Trigger Divergent Early T Cell Responses

March 16, 2026
10:30 AM - 11:45 AM | CASPARY AUDITORIUM
  • View all upcoming events
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Conflict of Interest in Research