The body's first blush with a pathogen shapes how it will respond to vaccines. New evidence clarifies how this phenomenon works, mechanistically.

A diverse immune response hinges on naive B cells mingling with high affinity ones in the late-stage germinal center. Whether that helps or hinders, however, depends on the virus.

Charles David Allis, a molecular biologist who shaped the field of chromatin biology, died on January 8 at the age of 71.

It's not just the number of mutations that matters. It's the failure to fix them too.

A novel method reduces the time required to identify novel antibiotic-producing DNA from weeks to days.

While most germinal centers shut down after a few weeks, some stay in business for more than six months. A new study helps explain why.

Breakthroughs in genetics, biochemistry, neuroscience, infectious disease, and drug development were a few of the year's highlights.

The library is offering new tools and training to support researchers operating under an updated NIH policy.

The findings shed a rare light on mitoribosomes, the unique ribosomes found within the cell's mitochondria.

People who receive monoclonal antibodies before vaccines may benefit from increased coverage, due to antibody feedback inhibition.