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Alexander Tomasz, a trailblazer in the study of multidrug-resistant microbes, has died

His work has been crucial for the development of new antibiotics, which are urgently needed in a world where multi-resistant superbugs are a major threat to public health.

Svetlana Mojsov wins the 2024 Lasker~DeBakey Clinical Medical Research Award

Mojsov’s discovery of GLP-1 and its critical role in the regulation of insulin secretion and blood glucose led to the development of a revolutionary new class of medicines.

Rockefeller University surpasses new federal safeguards for volunteers in clinical research

The Association for the Accreditation of Human Research Protection Programs once again commended Rockefeller’s standards and practices.  

Why a promising breast cancer drug doesn’t work—and how to improve it

A treatment that appears effective in cancers such as myelofibrosis consistently fails in breast cancer clinical trials. A new study explains why.

Cancer cells may be using lipids to hide from the immune system

New study demonstrates that one type of lipid is so critical for immune evasion that certain cancers cannot proliferate without them. Modulating intake of dietary lipids could open up an avenue for treatment.

New findings on TB could change how we treat inflammatory disorders    

The study explains why treatments for many autoimmune and inflammatory diseases raise the risk of contracting TB—and also upends long-held assumptions about what kicks off an immune response.      

This technique for studying cell receptors could have sweeping implications for drug development

Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors.

New insight into the protein mutations that cause Rett syndrome

Findings bolster the idea that the functions of this protein—MeCP2—are more centered on nucleosomes, rather than other forms of DNA.

Second genetic sensor for DNA methylation discovered

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA.