Neuron 82: 682-694 Incremental integration of global contours through interplay between visual cortical areas Minggui Chen, Yin Yan, Xiajing Gong, Charles D. Gilbert, Hualou Liang and Wu Li

Over the weeks following an invasion by a disease-causing microbe, the human immune system fine tunes its defenses, producing proteins called antibodies that are ever more precisely targeted at the invader. New research in Michel Nussenzweig’s Laboratory of Molecular Immunology helps explain how ...

Robert B. Darnell, Robert and Harriet Heilbrunn Professor and head of the Laboratory of Molecular Neuro-oncology, has been named a member of the National Academy of Sciences. Darnell is one of 84 newly elected members announced today by the Academy; an additional 21 foreign associates from 15 cou...

This land is your land   "Food, [Jesse Ausubel] told me, is a little like clothing. 'There are large companies that turn out the blue jeans and T-shirts we all wear. We don't mind large scale for that. But sometimes we all want a little something nicer, a little more fashionable. Even people with...

Proceedings of the National Academy of Sciences USA online: April 28, 2014 Structure of the branched intermediate in protein splicing Zhihua Liu, Silvia Frutos, Matthew J. Bick, Miquel Vila-Perelló, Galia T. Debelouchina, Seth A. Darst and Tom W. Muir

Cell 157: 636-650 Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function Ender Karaca, Stefan Weitzer, Davut Pehlivan, Hiroshi  Shiraishi, Tasos Gogakos, Toshikatsu Hanada, Shalini N. Jhangiani, Wojciech Wiszniewski, Marjorie Withers, Ian M. Camp...

Proceedings of the National Academy of Sciences USA online: April 24, 2014 A model for the generation and transmission of variations in evolution Olivier Rivoire and Stanislas Leibler

A football-shaped structure, known as the mitotic spindle, makes cell division possible for many living things. This piece of cellular architecture, responsible for dividing up genetic material, is in constant flux. The filaments that form it grow and shrink, while motor-like molecules burn energ...

A new tool, essentially a genetic navigation system that can help biologists identify connections and measure distances between human genes, has received an upgrade. Now, just as with Google Maps, anyone can access the Human Gene Connectome, without training in computational biology or the need t...

A young animal’s genes are not the only genes that determine its fate. The genetic identity of its caretakers matters too. Researchers suspect the interaction between the two can sway the fate of the young animal, but this complex dynamic is difficult to pin down in lab experiments. However, soci...