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Displaying 169 of 2858 articles.

Neurobiologist interested in memory to join Rockefeller faculty

by Wynne Parry, science writer Currently a postdoc at Stanford, Dr. Rajasethupathy will join the university as a tenure-track assistant professor and head of laboratory in May. She is the third new scientist to emerge from Rockefeller’s fall 2015 open recruitment process, making this year...

Do artificial sweeteners live up to the promise of sweetness without harm? An ongoing clinical study investigates

There was a time when Thomas Huber, a molecular biologist at The Rockefeller University, was drinking about 36 ounces of diet cola a day. More than a year ago, Huber, a research assistant professor in Thomas P. Sakmar’s Laboratory of Chemical Biology and Signal Transduction, became curious about ...

New insights into muscular dystrophy point to potential treatment avenues

The average healthy man is 54 percent muscle by mass, but people with muscular dystrophy, an incurable, genetic condition, have almost no muscle at terminal stages of the disease. New research from The Rockefeller University provides insights about what causes patients’ muscles to degenerate and ...

Researchers find new signs of stress damage in the brain, plus hope for prevention

Chronic stress can make us worn-out, anxious, depressed—in fact, it can change the architecture of the brain. New research at The Rockefeller University shows that when mice experience prolonged stress, structural changes occur within a little-studied region of their amygdala, a part of the brain...

New technique captures the activity of an entire brain in a snapshot

When it comes to measuring brain activity, scientists have tools that can take a precise look at a small slice of the brain (less than one cubic millimeter), or a blurred look at a larger area. Now, researchers at The Rockefeller University have described a new technique that combines the best of...

35 labs and counting: How the Robertson Therapeutic Development Fund speeds translational research at Rockefeller

by Alexandra MacWade, assistant editor Developing a new medical product is a complex, high-risk endeavor. Of the thousands of clinically promising concepts scientists formulate each year, only a small fraction move beyond the lab. The Robertson TDF was created to advance work that has gone beyon...

Researchers use new CRISPR-based strategy to replicate disease in cells

To explore in detail how specific genetic errors can lead to disease, scientists need to perform experiments in cells that carry these exact mutations. Now, the ability to create these cellular replicas using new genome editing technology has been facilitated thanks to work by Rockefeller Univers...

Nathaniel Heintz and Stanislas Leibler elected to the National Academy of Sciences

Nathaniel Heintz, James and Marilyn Simons Professor and head of the Laboratory of Molecular Biology, and Stanislas Leibler, Gladys T. Perkin Professor and head of the Laboratory of Living Matter, have been elected to the U.S. National Academy of Sciences. They are among 84 new national and 21 ne...

An experimental Alzheimer’s drug reverses genetic changes thought to spur the disease

Aging takes its toll on the brain, and the cells of the hippocampus—a brain region with circuitry crucial to learning and memory—are particularly vulnerable to changes that can lead to Alzheimer’s disease or cognitive decline. With the hope of counteracting the changes that can lead to these t...

In the News - Stat - Tessier-Lavigne

Scientists solve CRISPR's 'Energizer Bunny' problem   "'It works beautifully,' Tessier-Lavigne said. With standard CRISPR-Cas9, 6 percent to 35 percent of the edits were clean, without random insertions and deletions due to Cas9’s repeated cuts, but with their upgrade, the percentage of clean e...