Nucleolar Assembly of the Small Ribosomal Subunit

Event Details

Type

Friday Lecture Series

Speaker(s)

Sebastian Klinge, Ph.D., assistant professor and head, Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University

Speaker bio(s)

In a rapidly dividing yeast cell, 2000 ribosomes are made per minute to fulfill the cell’s metabolic requirements. While our understanding of protein synthesis is quite advanced, relatively little is known about how ribosomes themselves are assembled. Ribosome biogenesis is a highly orchestrated sequence of events requiring over 200 assembly factors and spanning three cellular compartments. Dr. Klinge’s laboratory aims to elucidate the sequence of events and molecular mechanisms responsible for the formation of both ribosomal subunits. He will describe recent studies examining the temporal order of assembly and the structures of the earliest intermediates of the small ribosomal subunit.

Dr. Klinge received his Ph.D. from the University of Cambridge in 2009. He performed postdoctoral research with Nenad Ban at the ETH Zurich before joining the faculty at Rockefeller University in 2013. Dr. Klinge is the recipient of several honors, including the 2016 NIH Director’s New Innovator Award. He is also a 2014 Rita Allen Foundation Scholar and received the 2014 HFSP Career Development Award.

Open to

Public

Host

Sean Brady

Reception

Refreshments, 3:15 p.m. - 3:45 p.m., Abby Lounge

Contact

Justin Sloboda

Phone

(212) 327-7785

Sponsor

Justin Sloboda
(212) 327-7785
jsloboda@rockefeller.edu

Readings

http://librarynews.rockefeller.edu/?p=5959