The rockefeller university

Event Details

Type

Friday Lecture Series

Speaker(s)

Xiaoliang "Sunney" Xie, Ph.D., Mallinckrodt Professor of Chemistry and Chemical Biology, Harvard University

Speaker bio(s)

DNA exists as single molecules in an individual cell. Consequently gene expression is stochastic. Single-molecule gene expression experiments in live single cells have allowed scientists to make quantitative descriptions and mechanistic interpretations. The fact that there are 46 different individual DNA molecules (chromosomes) in a human cell dictates that genomic variations occur stochastically and cannot be synchronized among individual cells. Recent developments in the ability to conduct single-cell and single-molecule measurements have made it possible to study genomic variations in new ways, opening opportunities to investigate and diagnose cancer, as well as to detect genetic disorders in newborns.

 

Dr. Xie received his Ph.D. from the University of California at San Diego in 1990, and did postdoctoral work at the University of Chicago. In 1992, Dr. Xie joined Pacific Northwest National Laboratory, where he later became a chief scientist. He moved to Harvard in 1999, and is also Cheung Kong Visiting Professor at Peking University and director of the Biodynamics Optical Imaging Center. Dr. Xie has made major contributions to the emergence of the field of single-molecule biophysical chemistry and its application to biology. His team also pioneered the development of coherent Raman scattering microscopy and single-cell whole genome sequencing. His honors include the Biophysical Society Founders Award, the NIH Director's Pioneer Award, the Sackler Prize for Physical Sciences, the Peter Debye Award in Physical Chemistry, and the Albany Prize in Medicine. Dr. Xie is a fellow of the American Academy of Arts and Sciences and a member of the National Academy of Sciences. 

Open to

Public

Host

Seth Darst, Ph.D.

Reception

Refreshments, 3:15 p.m. - 3:45 p.m., Abby Lounge

Contact

Linda Hanssler

Phone

(212) 327-7714

Sponsor

Linda Hanssler
(212) 327-7714
lhanssler@rockefeller.edu

Readings

http://librarynews.rockefeller.edu/?p=3975