Event Detail (Archived)

Transcription Factors and Genomic Architecture

The Cancer Biology Lecture

  • This event already took place in June 2015
  • Caspary Auditorium

Event Details

Type
Friday Lecture Series
Speaker(s)
Frank Grosveld, Ph.D., professor and head, department of cell biology; chair, research school, Medical Genetics Center Southwest Netherlands, Erasmus University Medical Center
Speaker bio(s)

Mechanisms of gene regulation, long range interactions and genome architecture will be discussed using hematopoietic development and differentiation as the biological system. A combination of proteomics, genomics and imaging techniques has been used to study the transcription factor network to generate hematopoietic stem cells. The primary focus will be on the complex formed by the transcription factors TAL1 and GATA and how they function in the hematopoietic pathway. This will be discussed in the context of 3D genome dynamics and the basic architecture of genome.
 
Dr. Grosveld studied biochemistry at the University of Amsterdam and obtained his Ph.D. from McGill University in 1976. After two postdoctoral periods he became head of the division of gene structure and expression at the National Institute for Medical Research, in the United Kingdom, in 1981. He moved to Erasmus University Rotterdam in 1993. Dr. Grosveld has been awarded the Jeantet Prize and the Spinoza Prize. He is a professor of the Dutch National Academy, a member of the Royal Dutch Academy of Sciences, and a fellow of the Royal Society of the UK.

Open to
Public
Reception
Refreshments, 3:15 p.m. - 3:45 p.m., Abby Lounge
Contact
Linda Hanssler
Phone
(212) 327-7714
Sponsor
Linda Hanssler
(212) 327-7714
lhanssler@rockefeller.edu
Readings
http://librarynews.rockefeller.edu/?p=3857