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St. Giles Laboratory of Human Genetics of Infectious Diseases

Jean-Laurent Casanova, M.D., Ph.D.

Levy Family Professor
Investigator, Howard Hughes Medical Institute
  • Genetics and Genomics
  • Immunology, Virology, and Microbiology
  • Mechanisms of Human Disease
  • Neurosciences and Behavior
  • Organismal Biology and Evolution
  • Stem Cells, Development, Regeneration, and Aging

News

A protein thought to play a supporting role in DNA replication actually facilitates the whole process

January 28, 2026
Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight that could inform research into cancer and other diseases.

In rare cases, autoantibodies can cause severe reactions to a live-attenuated virus Chikungunya vaccine that has been discontinued in the U.S.

January 26, 2026
A new study shows that preexisting autoantibodies in a small subset of the population can allow weakened vaccine viruses to escape control, explaining some adverse events tied to this one kind of Chikungunya vaccine, which is no longer available in the U.S.

Study on brain navigation reveals function of an unconventional electrical-signaling mode in neurons

January 21, 2026
New work in fruit flies uncovers an electrical trick that allows neurons to compute direction efficiently by juggling multiple signaling mechanisms. These findings could reframe our understanding of how some neurons operate.
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Upcoming Events

Intro to Python

January 29, 2026
9:00 AM - 5:00 PM | 305 WRB

HRGD Journal Club

January 29, 2026
12:00 PM - 1:00 PM | 110 RRB

Dorian Wind Quintet

January 29, 2026
7:30 PM - 9:30 PM | CASPARY AUDITORIUM
Recognized by critics, audiences, and colleagues alike for its polished and passionate performances, the Dorian Wind Quintet is known worldwide as one of chamber music’s pre-eminent and longest continuously active ensembles. The Quintet has traveled around the world – concertizing in 48 of the 50 United States and Canada, touring Europe eighteen…...
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  • Laboratories 74/90
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