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St. Giles Laboratory of Human Genetics of Infectious Diseases

Jean-Laurent Casanova, M.D., Ph.D.

Levy Family Professor
Investigator, Howard Hughes Medical Institute
  • Genetics and Genomics
  • Immunology, Virology, and Microbiology
  • Mechanisms of Human Disease
  • Neurosciences and Behavior
  • Organismal Biology and Evolution
  • Stem Cells, Development, Regeneration, and Aging

News

Why understanding stem cells lies as the root of treating diseases from psoriasis to cancer

December 4, 2025
Elaine Fuchs has spent decades uncovering why our bodies are so good at regenerating skin—and how we might harness that understanding to combat illness, hair loss, and perhaps even the aging process itself.

New model demonstrates how a dynamic mechanism regulates traffic through the nuclear pore complex

December 2, 2025
A new study reveals that nuclear pore complexes—tiny gateways in a cell’s nuclear membrane—are governed by dynamic action.

Scientists can finally answer an old question about cellular aging

December 1, 2025
Replicative aging of human cells, the result of telomere shortening, is slower at physiological oxygen than at atmospheric oxygen, a difference now shown to be due to low oxygen impairing the ATM kinase response to withered telomeres.
  • View all news

Upcoming Events

From Ancestry to Biochemistry in Steatotic Liver Disease

December 5, 2025
3:30 PM - 4:30 PM | CASPARY AUDITORIUM
The Joshua Lederberg Distinguished Lecture in Molecular Genetics

Self-Organization and Symmetry Breaking in Human Embryo and Models

December 8, 2025
4:00 PM - 5:00 PM | CARSON FAMILY AUDITORIUM (CRC)

Rare Sugar Probes to Identify Glycan Binding Proteins

December 9, 2025
4:00 PM - 5:00 PM | 116 ROCKEFELLER RESEARCH LABORATORIES, MSKCC, 430 E. 67TH ST.
  • View all upcoming events
  • Laboratories 74/90
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Conflict of Interest in Research