News & HighlightsNews
Norton Zinder, pioneering molecular geneticist, dies at 83
Norton D. Zinder, a geneticist and microbiologist whose research on the genetics of bacteria and on the properties of bacteriophages — viruses that infect bacteria — provided important information on the mechanisms of heredity, died Friday, February 3 after a long illness. He was 83. Zinder w...
Science 27: 436–441 (January 27, 2012)
Science 335: 436–441 Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel Stephen G. Brohawn, Josefina del Mármol and Roderick MacKinnon We present the crystal structure of human TRAAK at a resolution of 3.8 angstroms. The channel comprises two protomers, e...
Study in fruit flies reveals a gene affecting the ability to sleep
On the surface, it’s simple: when night falls, our bodies get sleepy. But behind the scenes, a series of complex molecular events, controlled by our genes, is hard at work to make us groggy. Now, research suggests that a newly identified gene known as insomniac may play a role in keeping us aslee...
Nature Genetics: January 22, 2012
Nature Genetics online: January 22, 2012 Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis Paul Delgado-Olguín, Yu Huang, Xue Li, Danos Christodoulou, Christine E. Seidman, J.G. Seidman, Alexander Tarakhovsky and Benoit G. Bru...
Cell Stem Cell: January 6, 2012
Cell Stem Cell 10: 63–75 Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Naoki Oshimori and Elaine Fuchs Hair follicle (HF) regeneration begins when communication between quiescent epithelial stem cells (SCs) and underlying mesenchymal d...
Nature Immunology: December 25, 2011
Nature Immunology online: December 25, 2011 B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen Irene Puga, Montserrat Cols, Carolina M. Barra, Bing He, Linda Cassis, Maurizio Gentile, Laura Comerma, Alejo Chorny, Meimei Shan...
Cell 147: 1615–1627 (December 23, 2011)
Cell 147: 1615–1627 The functional organization of cutaneous low-threshold mechanosensory neurons Lishi Li, Michael Rutlin, Victoria E. Abraira, Colleen Cassidy, Laura Kus, Shiaoching Gong, Michael P. Jankowski, Wenqin Luo, Nathaniel Heintz, H. Richard Koerber, C. Jeffery Woodbury and  David...
Science 344: 1675-1680
Science 344: 1675–1680 How a DNA polymerase clamp loader opens a sliding clamp Brian A. Kelch, Debora L. Makino, Mike O’Donnell and John Kuriyan We present structures for the ATP-bound state of the clamp loader complex from bacteriophage T4, bound to an open clamp and primer-template DNA. The s...
In the News -- NYT
"But the rule against posthumous awards has now been violated several times — most recently this month, when the prize in medicine was given to the widow of Dr. Ralph M. Steinman, a scientist at Rockefeller University in Manhattan who died of pancreatic cancer at age 68 on Sept. 30, three days be...
In the News -- NYT
"But the rule against posthumous awards has now been violated several times — most recently this month, when the prize in medicine was given to the widow of Dr. Ralph M. Steinman, a scientist at Rockefeller University in Manhattan who died of pancreatic cancer at age 68 on Sept. 30, three days be...
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