Science online: April 11, 2013 Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia Alexandre Bolze, Nizar Mahlaoui, Minji Byun, Bridget Turner, Nikolaus Trede, Steven  R. Ellis, Avinash Abhyankar, Yuval Itan, Etienne Patin, Samuel Brebner, Paul Sackstein, Anne Puel...

A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs. The antibiotic, Epimerox, targe...

Nature 496: 110-113 SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine Hong Jiang, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jintang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao and Hening Lin

Obama to unveil initiative to map the human brain   "A working group at the N.I.H., described by the officials as a 'dream team,' and led by Cori Bargmann of Rockefeller University and William Newsome of Stanford University, will be charged with coming up with a plan, a time frame, specific goals...

Good Day New York Book Club interviews Erec Stebbins   "Erec Stebbins is an award-winning researcher at Rockefeller University. In his spare time, he has written an absorbing thriller about an FBI agent tracking down home grown terrorists. The book is called The Ragnarök Conspiracy."

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research from C. David Allis’s laboratory at Rockefeller University may bring scientists closer to design...

Cell 153: 126-138 Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization Florian Klein, Ron Diskin, Johannes F. Scheid, Christian Gaebler, Hugo  Mouquet, Ivelin S. Georgiev, Marie Pancera, Tongqing Zhou, Reha-Baris Incesu, Brooks Zhongzh...

Molecular Cell 49:1121-1133 The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation Jaehoon Kim, Jung-Ae Kim, Robert K. McGinty, Uyen T.T. Nguyen, Tom W. Muir, C. David Allis and Robert G. Roeder

Science online: March 28, 2013 Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma Peter W. Lewis, Manuel M. Müller, Matthew S. Koletsky, Francisco Cordero, Shu  Lin, Laura A. Banaszynski, Benjamin A. Garcia, Tom W. Muir, Oren J. Becher and C. David Allis

Proceedings of the National Academy of Sciences USA online: March 27, 2013 A phase transition in the first passage of a Brownian process through a fluctuating boundary with implications for neural coding Thibaud Taillefumier and Marcelo O. Magnasco