The clearest picture to date of how two proteins determine the destiny of a stem cell that is genetically programmed to develop into either hair or skin epidermis is emerging with mouse embryos as models for human biology from the Howard Hughes Medical Institute at Rockefeller University. The sci...

Scientists at Rockefeller University have discovered how estrogen initiates physical changes in rodent brain cells that lead to increased learning and memory — a finding, the researchers contend, that illustrates the likely value of the hormone to enhance brain functioning in women. Their study, ...

Every minute, the human body replaces 300 million of its dying cells with new ones through the vital biological process known as cell division. When dividing and multiplying, a "parent" cell must segregate with exquisite precision each of its 46 chromosomes so that two "daughter" cells inherit al...

"Brute force biochemistry" still required to isolate novel proteins Since their fiery beginnings on earth over three billion years ago, bacteria have evolved some unusual strategies for dealing with the problems of life, a kind of odd bag of tricks specialized for survival. The most recent idiosy...

B cell chromatin study strikes physiological chord Some cells sing with the chorus, while others unwittingly achieve fame on their own. The immune system's B cell is a true diva that spends its early days preparing for the ultimate audition. Its repertoire of possible antibodies to invading micro...

Broad-based basic and clinical research program needed to better understand interactions of genes and environment "Jack Sprat could eat no fat, his wife could eat no lean," goes the classic children's nursery rhyme, implying that Jack's trim figure and his wife's portly profile were a conscious c...

Chua lab discovers protein that regulates early growth arrest An infant plant sleeps peacefully within its seed, entirely shielded from drought and other harsh conditions that might otherwise threaten its well-being. When the time comes at last to wake up and stretch its budding leaves, the young...

Nobel laureate, British cancer biology researcher elected ninth RU President The Rockefeller University announced today that its Board of Trustees has elected Sir Paul Nurse, Ph.D., as the ninth President of the university. Nurse currently is Chief Executive of Cancer Research UK, the world's lar...

Deadly coral toxin exposes ion pump's deepest secret Right now, in your body, tiny pumps in the fatty membranes surrounding all your cells are hard at work pushing select charged ions, such as sodium, potassium or calcium, through those membranes. Like a water pump in a high-rise apartment buildi...

"Quantum dots" may allow researchers to track proteins and cells in their natural environments Imagine if molecular and cell biologists could watch proteins and cells at work in their natural habitat in the same way that wildlife biologists observe animals in the wild. They'd sit back and witness...