The mountainous Chinese province of Yunnan is tucked into the country’s southwest corner, a scenic region that borders Burma, Laos and Vietnam. The province shares its rugged topography with the surrounding countries, but it shares a less favorable trait as well: a growing AIDS epidemic, driven b...

Each time a human cell divides it has to replicate three billion base pairs of DNA. All of the cell’s DNA must be copied once, but not more than once, within a very short period of time. But new research in yeast from Rockefeller University shows that instead of going about DNA replication in an ...

When an infection strikes, B cells act as the immune system’s tag-and-release team, hunting down the invading pathogen with incredible accuracy and labeling it with antibodies that inform other immune cells to destroy it. B cells are taught to recognize their prey inside tiny structures called ge...

Parasites have spent millions of years of evolution trying to outsmart the human immune system, and one of their tricks is to change their appearance so that the immune cells no longer recognize them. In the parasite Trypanosoma brucei, which causes African sleeping sickness, new research suggest...

HIV vaccine science has hit a bit of a wall. For a vaccine to be really effective, it should be able to recruit different areas of the immune system. It should get one set of immune cells, called helper T cells, to recognize the AIDS virus and spur on another set of immune cells, the killer T cel...

The National Academy of Sciences announced today that Rockefeller University scientist Jeffrey M. Friedman will receive the National Academy of Sciences’ Jessie Stevenson Kovalenko Medal — a medal and prize of $25,000 awarded every three years for important contributions to the medical sciences....

Dendritic cells coordinate and direct the body’s immune response, playing a crucial role in our ability to fend off disease. By processing molecules from invading pathogens — called antigens — they can present those molecules for other immune cells to recognize and attack. But researchers have...

Cell death during animal development acts like an eraser — sculpting organs, the nervous system, fingers and toes — by removing unnecessary or unneeded cells. There are a few different processes that regulate how and when cells die, but research from Rockefeller University identifies a new type ...

Plants might not get colds, but they do get viruses — and viral diseases in crops cause enormous economic damage each year. New research, however, suggests that plant “vaccines,” developed at Rockefeller University, may be a new way of helping fend off viral attackers. “Plants possess sever...

Since HIV was discovered in the early 1980s, scanning electron microscopes have been capturing images of the virus associated with different membranes of the cell they’ve infected. They can be seen stuck to the cell’s outer plasma membrane, as well as within membrane-enclosed structures called e...