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A Redoubt of Learning Holds Firm   "More broadly, [Paul Nurse] doesn’t fret about American dominance. That is just the way it is. Perhaps some cultural differences even accrue to the British side of the ledger. 'The U.S.A. has a very strong work ethic, and you keep a very close eye to the cutti...
Researchers demonstrate how ‘interfering’ RNA can block bacterial evolution
Bacteria may be simple creatures, but unlike “higher” organisms they have a neat evolutionary trick. When the going gets tough, they can simply pick up and incorporate a loose bit of genetic material from their environment. It’s instant evolution, no time-consuming mutations required. This pro...
Michael W. Young receives Massry Prize
Michael W. Young, Richard and Jeanne Fisher Professor and head of the Laboratory of Genetics, is being honored with the 2012 Massry Prize for his groundbreaking work on the molecular biology of circadian rhythms. Established by the Meira and Shaul G. Massry Foundation, the prize recognizes outsta...
Neuron 75: 585-592 (August 23, 2012)
Neuron 75: 585-592 Neuromodulatory state and sex specify alternative behaviors through antagonistic synaptic pathways in C. elegans Heeun Jang, Kyuhyung Kim, Scott J. Neal, Evan Macosko, Dongshin Kim, Rebecca A. Butcher, Danna M. Zeiger, Cornelia I. Bargmann and Piali Sengupta
Proceedings of the National Academy of Sciences USA online: August 20, 2012
Proceedings of the National Academy of Sciences USA online: August 20, 2012 Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro John W. Schoggins, Marcus Dorner, Michael Feulner, Naoko Imanaka, Mary  Y. Murphy, Alexa...
Cell 150: 764-779 (August 17, 2012)
Cell 150: 764-779 The BMP inhibitor coco reactivates breast cancer cells at lung metastatic sites Hua Gao, Goutam Chakraborty, Ai Ping Lee-Lim, Qianxing Mo, Markus  Decker, Alin Vonica, Ronglai Shen, Edi Brogi, Ali H. Brivanlou and Filippo G. Giancotti
Cell Host & Microbe 12: 177-186 (August 16, 2012)
Cell Host & Microbe 12: 177-186 CRISPR interference can prevent natural transformation and virulence acquisition during in vivo bacterial infection David Bikard, Asma Hatoum-Aslan, Daniel Mucida and Luciano A. Marraffini
Proceedings of the National Academy of Sciences USA online: August 13, 2012
Proceedings of the National Academy of Sciences USA online: August 13, 2012 Structural investigations of a Podoviridae streptococcus phage C1, implications for the mechanism of viral entry Anastasia A. Aksyuk, Valorie D. Bowman, Bärbel Kaufmann, Christopher  Fields, Thomas Klose, Heather A. Holda...
Protein proves vital in immune response to bacteria
A team of researchers led by scientists at Rockefeller University have discovered that a protein once thought to be mainly involved in antiviral immunity is in fact more important in fighting bacterial infections and could provide new mechanisms for treating diseases like tuberculosis, which is i...
Neuron 75: 437-450 (August 9, 2012)
Neuron 75: 437-450 Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy Konstantinos Charizanis, Kuang-Yung Lee, Ranjan Batra, Marianne  Goodwin, Chaolin Zhang, Yuan Yuan, Lily Shiue, Melissa Cline, Marina M. Scotti, Guangbin Xia, Ashok ...
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