News & HighlightsNews
Genetically driven gut feelings help female flies choose a mate
Even among flies, mating is a complicated ritual. Their elaborate, and entirely innate, courtship dance combines multiple motor skills with advanced sensory cues. Now, researchers at Rockefeller University have determined that the Abdominal-B (Abd-B) gene, previously known as the gene that sculpt...
Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington's Disease
Neuron 83(1):178-88 Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington's Disease Joshua L. Plotkin, Michelle Day, Jamys D. Peterson, Zhong Xie, Geraldine J. Kress, Igor Rafalovich, Jyothisri Kondapalli, Tracy S. Gertler, Marc Flajolet, Paul Greengard, Mihaela Sta...
Using geometry, researchers coax human embryonic stem cells to organize themselves
About seven days after conception, something remarkable occurs in the clump of cells that will eventually become a new human being. They start to specialize. They take on characteristics that begin to hint at their ultimate fate as part of the skin, brain, muscle or any of the roughly 200 cell ty...
Potential Alzheimer’s drug prevents abnormal blood clots in the brain
Without a steady supply of blood, neurons can’t work. That’s why one of the culprits behind Alzheimer’s disease is believed to be the persistent blood clots that often form in the brains of Alzheimer’s patients, contributing to the condition’s hallmark memory loss, confusion and cognitive ...
Sequencing efforts miss DNA crucial to bacteria’s disease causing power
Genomic sequencing is supposed to reveal the entire genetic makeup of an organism. For infectious disease specialists, the technology can be used to analyze a disease-causing bacterium to determine how much harm it is capable of causing and whether or not it will be resistant to antibiotics. But ...
Jean-Laurent Casanova to receive 2014 Robert Koch Award
Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, has been awarded the 2014 Robert Koch Award from the Berlin, Germany based Robert Koch Foundation. Casanova shares the prize with Alain Fischer from the Collège de France and Imagine Institute and th...
The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment (June 22, 2014)
Nature Cell Biology online: June 22, 2014 The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment Mu He, Radhika Subramanian, Fiona Bangs, Tatiana Omelchenko, Karel F. Liem Jr, Tarun M. Kapoor & Kathryn V. Anderson
Science 344, 1401-1405
Science 344, 1401-1405 | Newswire HIV-1–induced AIDS in monkeys Theodora Hatziioannou,Gregory Q. Del Prete, Brandon F. Keele, Jacob D. Estes, Matthew W. McNatt, Julia Bitzegeio, Alice Raymond, Anthony Rodriguez, Fabian Schmidt, C. Mac Trubey, Jeremy Smedley, Michael Piatak Jr., Vineet N. KewalRam...
New monkey model for AIDS offers promise for medical research
HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It does not readily infect species other than its usual hosts — humans and chimpanzees. While this would qualify as good news for most mammals, for humans this fact has made the search for effective treatments and vac...
Structural biologist, focused on cell transport machinery, to join faculty
Jue Chen, a structural biologist whose research focuses on transporter proteins that act as the cell’s pumping machinery, will join The Rockefeller University as professor and head of laboratory in July. Chen, currently a tenured professor of biology at Purdue University in Indiana and a Howard H...
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