For most people with Parkinson’s disease, the only relief from the tremors, rigidity and impaired movement associated with the progressive loss of their motor skills is a drug called L-DOPA. But as the disease progresses, L-DOPA can cause prominent side effects that counteract its effectiveness. ...

Researchers studying anthrax knew they were onto something when they discovered an opponent the bacterium couldn’t outwit. Probing a bit deeper, they discovered this was because the attacker was interacting with something anthrax requires to survive: a carbohydrate in its cell wall. Now, in a stu...

Like fine china and crystal, which tend to be used sparingly, stem cells divide infrequently. It was thought they did so to protect themselves from unnecessary wear and tear. But now new research from Rockefeller University has unveiled the protein that puts the brakes on stem cell division and s...

In a study that could open up the field of virology to an entirely new suite of possibilities and that paves the way for future drug research, scientists at Rockefeller University and the Aaron Diamond AIDS Research Center have pinned down a molecule on the surface of human cells that helps keep ...

The French Nobel laureate Jacques Monod famously said, “What’s true for E.coli is true for an elephant.” With this in mind, researchers at Rockefeller University set out to determine the function of Tel2, a protein originally found in yeast where it maintains the length of chromosome tips ca...

Everything that goes in and out of a cell’s nucleus must pass through one of its nuclear pores. In the second nuclear pore study to come out of Rockefeller University in as many months, researchers have determined the crystal structure of one of the pore’s main components and used it to propose ...

Dendritic cells are responsible for directing the body’s immune response, and they’re activated through receptors on their surfaces. Now, in research that may have implications for novel disease therapies, Rockefeller University scientists have shown that the balance of two different versions of...

By pitting two forces — hunger and circadian rhythms — against each other, researchers at Rockefeller University have identified the region of the brain that first registers changes in food availability. The research, in mice, suggests that shifting the timing of a meal increases mental alertnes...

Animals and insects communicate through an invisible world of scents. By exploiting infrared technology, researchers at Rockefeller University just made that world visible. With the ability to see smells, these scientists now show that when fly larvae detect smells with both olfactory organs they...

Cells know that size matters, especially when it comes to the nucleus. In the early 1900s, German scientists first proposed that the size of a nucleus is always proportional to the size of its cell. Now, more than a century later, researchers at Rockefeller University show that an active mechanis...