News & HighlightsNews
Mammalian protein plays unexpected role in cell division, and perhaps cancer
The French Nobel laureate Jacques Monod famously said, “What’s true for E.coli is true for an elephant.” With this in mind, researchers at Rockefeller University set out to determine the function of Tel2, a protein originally found in yeast where it maintains the length of chromosome tips ca...
New model of a nuclear pore complex is based on crystal structure of its key component
Everything that goes in and out of a cell’s nucleus must pass through one of its nuclear pores. In the second nuclear pore study to come out of Rockefeller University in as many months, researchers have determined the crystal structure of one of the pore’s main components and used it to propose ...
Altering the balance of immune-cell receptors could help treat cancer and autoimmune diseases
Dendritic cells are responsible for directing the body’s immune response, and they’re activated through receptors on their surfaces. Now, in research that may have implications for novel disease therapies, Rockefeller University scientists have shown that the balance of two different versions of...
Two forces of arousal converge on the "satiety center" of the brain
By pitting two forces — hunger and circadian rhythms — against each other, researchers at Rockefeller University have identified the region of the brain that first registers changes in food availability. The research, in mice, suggests that shifting the timing of a meal increases mental alertnes...
New method enables scientists to see smells
Animals and insects communicate through an invisible world of scents. By exploiting infrared technology, researchers at Rockefeller University just made that world visible. With the ability to see smells, these scientists now show that when fly larvae detect smells with both olfactory organs they...
Active mechanism locks in the size of cell's nucleus
Cells know that size matters, especially when it comes to the nucleus. In the early 1900s, German scientists first proposed that the size of a nucleus is always proportional to the size of its cell. Now, more than a century later, researchers at Rockefeller University show that an active mechanis...
Most carriers of Fanconi anemia genes are not at a higher risk of cancer
For almost 50 years, Fanconi anemia has been associated with leukemia. Not just among those who have the genetic disorder but among their family members, whose genes, they were told, made them highly susceptible to a variety of malignancies. But a new study to examine links between 13 specific Fa...
New method exploits old mechanism to turn genes on and off at will
Since our ancestors first harnessed fire, we’ve used heat to cook burgers, forge steel and power rockets. Now, Rockefeller University researchers are using heat for another purpose: turning genes on and off at will. By exploiting the heat shock response, an ancient mechanism that protects cells f...
Cells use Velcro-like mechanism to keep viruses from spreading
Like mobsters, cells keep their friends close and their enemies — at least some of them — closer. According to new results from HIV researchers at Rockefeller University, one way that human cells prevent certain viruses from raging out of control is by blocking new viral particles from ever leav...
Small experience during critical period alters brain
Unlike the circuitry of the visual system, that of the olfactory system was thought to be hardwired: Once the neurons had formed, no amount of sensory input could change their arrangement. Now researchers at Rockefeller University and their collaborators have upturned this scientific dogma by sho...
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