News & HighlightsNews
Scientists discover an unexpected influence on dividing stem cells’ fate
When most cells divide, they simply make more of themselves. But stem cells, which are responsible for repairing or making new tissue, have a choice: They can generate more stem cells or differentiate into skin cells, liver cells, or virtually any of the body’s specialized cell types. As r...
Encouraging clinical results for an antibody drug to prevent or treat HIV
A new biologic agent—the most potent of its kind so far—is showing early promise as part of a potential new strategy for treating HIV. The drug, known as 10-1074, may also offer a new way to prevent viral infection in people who are at high risk to acquire HIV, the virus that causes AIDS. ...
Atomic-scale view of bacterial proteins offers path to new tuberculosis drugs
With the first detailed analysis of a cellular component from a close relative of the pathogen that causes tuberculosis, Rockefeller scientists are suggesting strategies for new drugs to curb this growing health problem. Each year, nearly half a million people around the world are infected with m...
Discovery helps explain why only some people develop life-threatening dengue infections
For most people who contract it, dengue fever is a relatively mild-mannered disease—at least the first time around. For some, however, a subsequent infection by the virus unleashes a vicious and potentially deadly illness. New research from a team based at The Rockefeller University has begun t...
Study reveals the structure of a protein crucial for DNA replication
Our DNA contains instructions crucial for virtually all forms of life on this planet. But for life to propagate, this blueprint must be copied and passed on to future generations. New findings describing the structure of a key molecule involved in DNA replication place another piece in the puzzle...
Researchers explore how protein production gets distorted in skin cancer
Each cell in the body follows a strict protocol for manufacturing the proteins it needs to function. When a cell turns cancerous, however, its protein production goes off script. A new study led by researchers at the Rockefeller University takes a close look at one way in which this procedure goe...
Antibody combination puts HIV on the ropes
Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body’s ability to control it. But a small group of infected individuals—called elite controllers—possess immune systems capable of defeating the ...
MacKinnon lab charts the anatomy of three molecular channels
Using a state-of-the-art imaging technology in which molecules are deep frozen, scientists in Roderick MacKinnon’s lab at Rockefeller University have reconstructed in unprecedented detail the three-dimensional architecture of three channels that provide a path for specific types of ions to travel...
New research offers clues into how the brain shapes perception to control behavior
What you see is not always what you get. And that, researchers at The Rockefeller University have discovered, is a good thing. “Every time you move your eye, the whole world moves on your retina,” says Gaby Maimon, head of the Laboratory of Integrative Brain Function. “But you don’t perce...
Scientists learn how to ramp up microbes’ ability to make memories
Some microbes can form memories—although, inconveniently for scientists who study the process, they don’t do it very often. Rockefeller University researchers and their colleagues at the University of California, Berkeley, have found a way to make bacteria encode memories much more frequently...
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