News & HighlightsNews
Lysin therapy offers new hope for fighting drug-resistant bacteria
Increasingly, bacteria do not succumb to antibiotics. Rockefeller researchers have developed a new class of antimicrobial drug, lysin, with one compound showing promising results in a clinical trial—suggesting that an alternative to antibiotics may be on the horizon.
In simple bacteria, scientists find new evidence of complex immunity
Bacteria use a multifaceted immune response to get rid of invading DNA. In a new study, researchers identify an enzyme that can destroy foreign genetic material capable of evading a microbe’s first line of defense.
Enzyme structure reveals how DNA is opened up for transcription
DNA’s two strands must be separated before its code can be read, or transcribed. By studying the structure of the enzyme RNA polymerase, researchers have elucidated how DNA unwinds and becomes legible.
Study identifies genetic mutation responsible for tuberculosis vulnerability
Scientists discovered a genetic variant that greatly increases a person’s likelihood of developing tuberculosis. Their research elucidates how this mutation affects the immune system, and points to a possible treatment for people with the disease.
Year in review: 10 science stories to remember
Rockefeller researchers accomplished a lot this year. We look back at 10 of the most exciting science stories of 2018.
Study explains how geckos gracefully gallop on water
Geckos are amazingly agile. In addition to running across land and up trees, the animals can prance across the surface of water. A new study reveals how they do it.
Shape-shifting protein protects bacteria from invaders
Researchers have discovered how bacteria manage to destroy enemy DNA, while keeping their own genetic material safe.
First mapping of cells in the early human placenta to advance research on problem pregnancies
Scientists have made the first comprehensive inventory of cells present in the human placenta of the first trimester, a stage when many pregnancy complications are thought to arise. The findings could fuel new research on conditions such as preeclampsia and pre-term birth.
New method for studying gene expression could improve understanding of brain disease
By analyzing gene expression patterns, researchers have identified previously unknown distinctions between mouse and human neurons. They have also developed a new way to track cellular changes associated with brain disorders.
Mosquito genome opens new avenues for reducing bug-borne disease
Researchers have assembled a new and improved DNA catalogue for the mosquito Aedes aegypti. This tool will help researchers understand the insect’s biology, and may lead to new strategies for preventing diseases like Zika and dengue.
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