Studying microscopic worms, Rockefeller scientists have identified a brain circuit that drives repetitive behavior—providing potential clues for understanding some human psychiatric conditions.

In many cancer patients who have been treated with immunotherapy, the tumor comes back. New research identifies the cells responsible for thwarting the treatment and offers new insights into how they do it.

Researchers successfully modified immune cells to produce antibodies that fight HIV. This strategy could eventually be used to develop a vaccine against the virus, among other conditions.

Using new imaging technology, researchers can now record the activity of large populations of brain cells with unprecedented speed, and at new depths.

Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.

Researchers have discovered a new compound that helps fortify the intestine's inner lining, which becomes porous in inflammatory bowel diseases.  

Studying a brain region involved in memory, researchers discovered a set of neurons that help mice control their appetite.

Scientists still have a lot to learn about the processes that trigger cell division, partly because they happen so quickly. A new chemical probe will make it possible to capture the workings of one of the key players.

Some cancers have been traced to changes in histones, proteins responsible for packaging DNA and regulating genes. Now, research from Rockefeller scientists shows that, among tumors, mutations to these proteins are a lot more common than previously suspected.

Scientists discovered a protein that plays a crucial role in regulating fatty acids, the molecules that make up body fat. This research could lead to new options for treating people with diseases associated with fatty acid buildup.