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Observing Proteins and Cells in the Wild
"Quantum dots" may allow researchers to track proteins and cells in their natural environments Imagine if molecular and cell biologists could watch proteins and cells at work in their natural habitat in the same way that wildlife biologists observe animals in the wild. They'd sit back and witness...
Search for cholesterol absorption genes narrows to two chromosome regions
Findings with lab mice may lead to novel cholesterol-lowering drugs against heart disease Two people eat the same egg, cheese and ham muffin for breakfast, yet one absorbs significantly more cholesterol into his or her blood than the other. Why? The answer, and all of its implications for combat...
First quantum dots applied to living organism
"The most exciting, and beautiful, scientific images I have ever seen" Quantum dots are nano-sized crystals that exhibit all the colors of the rainbow due to their unique semiconductor qualities. These exquisitely small, human-made beacons have the power to shine their fluorescent light for month...
"Outlaw" organism turns informant
African trypanosome source of scientific insight In a critical scene in the film remake of the classic 1960s TV series "The Fugitive," actor Harrison Ford sheds his coat and replaces it with another. This simple deception allows him to escape detection by the swarm of police officers trailing him...
Noise inner life cells
Process of "reading" genes not perfectly predictable Within the smoothly operating factory that is the cell, tiny molecular machines carry out their tasks with order and certainty. Or at least that's what many scientists once believed. In a recent issue of Science, researchers at The Rockefeller ...
Wrong Proteins Targeted in Battle Against Cancer?
Lasker recipient James E. Darnell contends drug developers should focus more on "transcription factor" proteins Researchers may be looking for novel cancer drugs in the wrong places, says Rockefeller University Professor James E. Darnell Jr., M.D., in an article in this month's Nature Reviews Ca...
"CAF" protein mystery solved by AIDS researchers
Blood proteins shown to thwart HIV provide clues to potential new treatment Acclaimed AIDS researcher David Ho, M.D., a Rockefeller University Irene Diamond Professor who heads the Aaron Diamond AIDS Research Center (ADARC), and his research team, have discovered that several natural proteins -a...
Lasker Award Honors Rockefeller University's James Darnell
"Special Achievement in Medical Science" recognizes a groundbreaking researcher, influential writer and mentor James E. Darnell Jr., M.D., the pioneering researcher in the field of gene regulation — who has nurtured the careers of over 100 young, talented scientists — was honored today with the...
One gene, two important proteins
Researchers discover gene variation in cancer-causing "STAT" family encodes two —not one—functional proteins When the Human Genome Project first revealed last year that humans possess only an estimated 30,000 genes — fives times more than a mustard weed plant — the fact that many of our g...
Rockefeller researchers provide the first functional evidence for mammalian pheromone receptors
Pheromones — chemical signals that influence social and reproductive behaviors — have been studied since the 1950s, but the molecules in the mammalian nervous system that actually detect pheromones have remained elusive. Now, a team of researchers, led by The Rockefeller University's Peter Momb...
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