In equatorial Africa, a region of the globe known as the “lymphoma belt,” children are ten times more likely than in other parts of the world to develop Burkitt’s lymphoma, a highly aggressive blood cancer that can be fatal if left untreated. That area is also plagued by high rates of malaria,...

Jules Hirsch, an early leader in the study of human metabolism, died at age 88 in Englewood, New Jersey, after a long illness. His research, conducted at The Rockefeller University, helped establish the biological underpinnings of obesity, challenging the notion that the disease results from a la...

Agata Smogorzewska, a physician-scientist and head of the Laboratory of Genome Maintenance, has been promoted to associate professor, effective July 1. Smogorzewska came to Rockefeller as a faculty member in 2009 to study DNA repair processes that occur during cellular replication. “The genome ...

As Parkinson’s disease progresses in patients, a puzzling dichotomy plays out in their brains. One set of neurons degenerates, while a similar population nearby is spared the same degree of damage. Why the difference? An answer to this question could clear the way for preventions and treatments f...

Ice Bucket Challenge money distributed to ALS researchers   "In New York, Dr. Robert Darnell is one of the beneficiaries. The New York Genome Center, where he is the president and scientific director, received $2.5 million in challenge money from the ALS Association. Half of that money came from ...

Dividing cells are prone to errors, and so they must be prepared to summon sophisticated emergency systems to deal with potential damage. One type of division-derailing mishap can occur when assault by certain chemicals causes two strands of DNA to permanently connect when they shouldn’t, in what...

Our brains are constantly barraged with sensory information, but have an amazing ability to filter out just what they need to understand what’s going on around us. For instance, if you stand perfectly still in a room, and that room rotates around you, it’s terrifying. But stand still in a room a...

Bacteria have plenty of things to send out into world beyond their own boundaries: coordinating signals to other members of their species, poisons for their enemies, and devious instructions to manipulate host cells they have infected. Before any of this can occur, however, they must first get th...

Sustained by Science   "No artist stops working, and I think really dedicated scientists—unless their health doesn’t allow it—are the same way," Paul Greengard says. “We’re in a creative profession, so it never even occurred to me to stop."

It’s a basic principle of immunology: When a germ invades, the body adapts to that particular target and destroys it. But much remains unknown about how the immune system refines its defensive proteins, called antibodies, to most effectively zero in on that invader. Experiments at The Rockefeller...