News & HighlightsNews
New cell death pathway involved in sperm development
Heavy and bulky sperm would not be good swimmers. To trim down, sperm rely on cell death proteins called caspases, which facilitate the removal of unwanted cellular material and radically remodel these cells into their sleek, light shape. New research from scientists at the Howard Hughes Medical ...
Gene determines whether male body odor smells pleasant
To many, urine smells like urine and vanilla smells like vanilla. But androstenone, a derivative of testosterone that is a potent ingredient in male body odor, can smell like either — depending on your genes. While many people ascribe a foul odor to androstenone, usually that of stale urine or st...
Rockefeller immunologist receives Lasker Award for Basic Medical Research
This year’s Albert Lasker Award for Basic Medical Research, the most prestigious American prize in science, honors Rockefeller University’s Ralph M. Steinman, who discovered dendritic cells, the preeminent component of the immune system that initiates and regulates the body's response to foreign...
Dendritic cells stimulate production of immune-repressing T cells
Regulatory T cells (also known as T regs) suppress some of the immune system’s more inappropriate responses, preventing it from attacking the body’s own tissues and stifling its activity once invading microbes have been fought off. But while researchers knew that these cells could be exploited f...
Construction begins on new Collaborative Research Center
After nearly two years of planning, construction is under way on The Rockefeller University’s new Collaborative Research Center, a building and renovation project that will transform two historic limestone and masonry buildings into modern open-plan laboratories connected by a dramatic six-story ...
A global view: Researchers build microRNA atlas
Building a comprehensive microRNA expression atlas is not easy. Just ask the Rockefeller University scientists who, in a massive collaborative effort involving 50 investigators from six countries, led the project. In three years, they catalogued microRNA expression patterns in more than 250 healt...
Core tenets of the "histone code" are universal
In one of biology’s most impressive engineering feats, specialized proteins called histones package some six-and-a-half feet of human DNA into a nucleus that averages just five microns in diameter. That’s only 0.0001969 inches. DNA wraps around histone proteins, which are then chemically modifie...
Common immune cell marker shown to be off target
A marker that scientists have depended on for over 15 years to pick out a group of immune cells in the skin has been misidentifying them, Rockefeller University scientists report. In order for scientists who study psoriasis and other skin disorders to understand the inner workings of disease, the...
From frogs to humans, brains form the same way
It’s a critical juncture in an embryo’s development: the moment that a brain and nervous system begin to form from a mass of unspecialized cells. Scientists had believed that mammals and amphibians, distinctly different animals, have distinctly different developmental patterns when it comes to t...
Food supply affects bacteria's response to temperature
As a population of bacteria grows, it can become desperate. When their food supply dwindles, bacteria must either forage for new sources of nutrients or slow their metabolism. That’s why, at a critical bacterial concentration,Escherichia coli use a chemical signal to collectively swim from warm a...
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