Intestinal Stem Cells and their Interactions with the Microbiome
Event Details
- Type
- Stem Cell Biology Seminars
- Speaker(s)
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Jeffrey Gordon, M.D., Dr. Robert J. Glaser Distinguished University Professor, Washington University in St. Louis
- Speaker bio(s)
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Jeffrey Gordon, MD is the Dr. Robert J. Glaser Distinguished University Professor at Washington University in St. Louis. He received his A.B. from Oberlin College and M.D. from the University of Chicago. After completing his clinical training in internal medicine and gastroenterology, and doing a post-doctoral fellowship at the NIH, he joined the faculty at Washington University where he has spent his entire career, first as a member of the Departments of Medicine and Biological Chemistry, then as Head of the Department of Molecular Biology and Pharmacology and now as Founding Director of the University’s interdepartmental Edison Family Center for Genome Sciences and Systems Biology. His group has used interdisciplinary approaches for defining mechanisms that underlie the assembly, expressed functions, and host effects of human gut microbial communities. His group’s translational studies, which include long-standing collaborations with Tahmeed Ahmed at the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), combine gnotobiotic animal models with characterization of the microbiomes and physiologic features of the very human populations whose microbiomes have been introduced into the animal models. This approach has allowed them to identify therapeutic targets in order to deliberately alter microbiome properties under conditions where postnatal microbial community assembly have been perturbed, as exemplified by their discovery and subsequent randomized controlled clinical trials of microbiome-directed therapeutic foods for childhood undernutrition. He is a member of the National Academy of Sciences, National Academy of Medicine, American Academy of Arts and Sciences and the American Philosophical Society. He has had the privilege of being the research mentor to 148 PhD students and post-doctoral fellows since his lab was established.
- Open to
- Tri-Institutional