The rockefeller university

Event Details

Type

Friday Lecture Series

Speaker(s)

Helen Hobbs, M.D., professor of internal medicine and molecular genetics, University of Texas Southwestern Medical Center; investigator, Howard Hughes Medical Institute

Speaker bio(s)

Helen H. Hobbs is an HHMI Investigator and Professor at UT Southwestern. With Jonathan Cohen, she has used human genetics to identify variants of large effect sizes that alter plasma levels of Lp(a) [APOA], LDL-cholesterol (ABCG5/ABCG8, LDLRAP, PCSK9, NPC1L1, ANGPTL3), and triglyceride (ANGPTL3,-4,-8). She also discovered the two most impactful genetic differences conferring risk of steatotic liver disease (PNPLA3, TM6SF2). Gene discovery is the starting point for studies elucidating the pathways disrupted by the defective genes she identifies. She is a member of the National Academy of Sciences (2007) and received the Breakthrough Prize in Life Sciences (2016).

Open to

Tri-Institutional