Christian de Duve, 95, dies; Nobel-winning biochemist   "[Dr. de Duve] discovered the lysosome, a tiny sack filled with enzymes that functions like a garbage disposal, destroying bacteria or parts of the cell that are old or worn out. His discoveries helped unravel the biology of Tay-Sachs diseas...

Cell online: May 1, 2013 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L. Gaffney, Thomas Zillinger, Artem A. Serganov, Yizhou Liu, Roger A. Jones, Gunther Hartmann, Thomas T...

Molecular Psychiatry 18: 943-950 The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons V. Lanoue, A. Usardi, S.M. Sigoillot, M. Talleur, K. Iyer, J. Mariani, P. Isope, G. Vodjdani, N. Heintz and F. Selimi

Proteins, unlike diamonds, aren’t forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University and the Howard Hughes Medical Institute have identified a new way that the cell’s pr...

Cell 153: 614-627 Proteasome regulation by ADP-ribosylation Park F. Cho-Park and Hermann Steller

Nature online: April 24, 2013 Random convergence of olfactory inputs in the Drosophila mushroom body Sophie J. C. Caron, Vanessa Ruta, L. F. Abbott and Richard Axel

The American Academy of Arts and Sciences announced its new class of members today, including two Rockefeller University researchers. Marc Tessier-Lavigne, Rockefeller president, Carson Family Professor and head of the Laboratory of Brain Development and Repair, and Jeffrey M. Friedman, Marilyn M...

Bring your child to work. In celebration of national Take Your Child to Work Day, Human Resources will host activities for 8- to 12-year-olds from 9 a.m. to 3 p.m. on April 25. Children must be registered by April 19 and must be accompanied by an adult to attend. Space is limited. For more inform...

By Zach Veilleux After nearly five years of construction, the final piece of the north campus modernization process is now complete and opens to the campus this month. The Welch Hall refurbishment, which began in January 2011, has finished on time and on budget and will link the north and south p...

by LESLIE CHURCH You don’t always know you’re making history when it’s happening. But it’s a good idea to hang on to all the evidence, just in case. That’s exactly what Merrill W. Chase did when he began collecting instruments invented at Rockefeller throughout the twentieth century. And ...