Developing neurons tend to play the field, making more connections than they will ever need. Then the weakest are cut. But Rockefeller University scientists now show that neurons in young zebrafish — vertebrates, like humans — behave differently: They immediately find a cluster of specialized ce...

Sometimes, small changes do add up. In the case of addictive diseases, tiny variations in a few genes can increase or decrease the likelihood of some people developing a dependency on heroin. Now, by examining a select group of genetic variants in more than 400 former severe heroin addicts, Rocke...

A simple blood test capable of predicting if a person might develop Alzheimer’s disease is within sight, and could eventually be used to help scientists reverse onset of the disease in those most at risk. According to new research by Rockefeller University scientists and their colleagues at Colum...

No child aspires to a lifetime of addiction. But their brains might. In new research to appear online in the journal Neuropsychopharmacology today, Rockefeller University researchers reveal that adolescent brains exposed to the painkiller OxyContin can sustain lifelong and permanent changes in th...

C. Erec Stebbins, associate professor at The Rockefeller University, has been awarded an inaugural EUREKA grant from the National Institutes of Health for a project aimed at exploiting a bacteria-based “nanosyringe” as a means of delivering proteins into specific cells for therapeutic purposes. ...

Vitamin D is the key to preventing rickets and osteoporosis, but Rockefeller University scientists suspect it may also play a role in heading off atherosclerosis in people with chronic kidney disease. In a new clinical study, investigators at The Rockefeller University Hospital are examining pati...

Psoriasis, one of humanity’s oldest known diseases, has also been one of its most misunderstood. But in a new study that could change researchers’ perspective of the skin disorder and potentially lead to powerful new drug targets, Rockefeller University scientists have found that the source of p...

Amid concerns about the rising number of new tuberculosis cases worldwide, researchers at Rockefeller University and their collaborators have reexamined and disproved a theory that describes how a potent class of antibiotics kills a deadly form of bacteria. The findings, which will appear in this...

The richer you are, the more of the world’s resources you can afford to consume. But in many parts of the world, rising incomes are not having the proportionate effect on energy consumption, croplands and deforestation that one might expect, a new 25-year study shows. By examining a variety of go...

When a cell begins to multiply in a dangerously abnormal way, a series of death signals triggers it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the...