News & HighlightsNews
Large-scale survey of clinical research participants shows mostly positive experiences
A multi-center survey of close to 5,000 volunteers who enrolled in clinical research studies, the first of its kind, shows that by and large participants feel valued and respected by investigators. But although many gave high marks to the research teams’ trustworthiness and ability to explain the...
Gene is linked to deadly runaway fungal infection
For most people, a fungal infection like athlete’s foot means a simple trip to the drugstore and a reminder to bring shower shoes to the gym. But in very rare cases, fungal infections can spread below the skin’s surface and onto the lymph nodes, bones, digestive tract or even the brain. Research...
New technique in RNA interference cuts time and cost in genetic screens
There is a new contender in the field of gene discovery, and it’s giving knockout mice a run for their money. Researchers at The Rockefeller University have shown that a new technique using RNA interference is able to find genes that cause epidermal tumor growth in months rather than the decades ...
Researchers find molecule that causes sunburn pain
The painful, red skin that comes from too much time in the sun is caused by a molecule abundant in the skin’s epidermis, a new study published in the Proceedings of the National Academy of Sciences shows. Blocking the molecule, called TRPV4, greatly protects against the painful effects of sunburn...
Scientists identify gene that regulates stem cell death and skin regeneration
Stem cells, known for their ability to self-renew and differentiate into any kind of tissue, are considered by many scientists in the field to be immortal. But there are signs that programmed death of stem cells is important for their regulation. New research from scientists at Rockefeller Univer...
Mutant mosquitoes lose their appetite for humans
What draws a mosquito to bite its host has long been studied from the perspective of the victim — uncovering which smells and chemicals lure the insect in. But researchers at Rockefeller’s Laboratory of Neurogenetics and Behavior, headed by Robin Chemers Neustein Professor Leslie Vosshall, are a...
Scientists discover new way protein degradation is regulated
Proteins, unlike diamonds, aren’t forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University and the Howard Hughes Medical Institute have identified a new way that the cell’s pr...
Scientists discover gene mutation that causes children to be born without spleen
The spleen is rarely noticed, until it is missing. In children born without a spleen, that doesn’t happen until they become sick with life-threatening bacterial infections, often within their first year of life. An international team of researchers led by scientists from Rockefeller’s St. Giles ...
Scientists use Nature against Nature to develop an antibiotic with reduced resistance
A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs. The antibiotic, Epimerox, targe...
Mechanism of mutant histone protein in childhood brain cancer revealed
Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research from C. David Allis’s laboratory at Rockefeller University may bring scientists closer to design...
View
View