News & HighlightsNews
Leukemia drug Gleevec slows accumulation of major component of senile plaques in cell studies and in guinea pigs
Gleevec, the breakthrough drug for treating chronic myologenous leukemia (CML) and gastrointestinal stromal tumors, slowed the accumulation of the major protein component of senile plaques that characterize Alzheimer's disease, in laboratory cultures of mouse brain cells and guinea pigs. The find...
Salmonella bacterium uses potent molecular "staples" to change structure of cells it infects
Salmonella, a well-known food-borne bacterium, uses protein "staples" to restructure the shape of the gut cells it invades, forcing these cells to flow around the bacteria and engulf them, researchers at Rockefeller University have discovered. The research, published in the September 26 issue of ...
Measuring early antibody aptituteds
Rockefeller University study suggests system "checkpoint failure" as one possible cause of autoimmunity Parents and educators pay close attention to preschoolers' aptitudes. Recognition of abilities, or potential difficulties, helps garner proper support for the youngsters as they begin their for...
Building hair from the ground up
Scientists show how development of hair depends on development of the hair channel There's more to a building than the materials that comprise it; equally important is the foundation that underlies and supports the main structure. Similarly, researchers at The Rockefeller University and the Howar...
Researchers close in on scientific definition of arousal
For scientists in the field of neurobiology, defining the factors that influence the arousal of brain and behavior is a "Holy Grail." Research published by Rockefeller University scientists in the Aug. 11 issue ofProceedings of the National Academy of Sciences Early Edition is the first to give a...
Rockefeller University researchers identify protein modules that "read" distinct gene "silencing codes"
Since the time when humans first learned to record their thoughts in written form, codes have kept sensitive information from prying eyes. But conveying information through a code requires someone who can read it as well as write it. The same is true for one of nature's methods for transmitting i...
Obese mice provide clues to natural system that puts brakes on obesity
First gene discovered that is switched on only in fat cells of obese mice A gene that gets switched on only in the fat cells of obese mice may be a key to preventing obesity in humans, according to new research at The Rockefeller University in New York City and the Joslin Diabetes Center in Bosto...
From creatures of the dark to photosynthesizing green beings
How plant seedlings respond to light A plant born into darkness, underneath a blanket of soil and leaves, will grow long and thin, its spindly stem stretching up towards the hidden sun. When at last it reaches the light, the plant will sprout green leaves, thicken its stem and begin to breathe - ...
Genetic clues to stem cells' unlimited potential
Rockefeller research team completes first map of human embryonic "stemness" As an embryologist, Ali H. Brivanlou wants to know every genetic route taken by a small mass of undifferentiated, or unformed, embryonic cells as they develop into an organism. Now he knows. The first atlas, or map, of ge...
New clues to schizophrenia come from mice, humans
Gene linked to schizophrenia in humans may provide new target for drug treatment Improper signaling by a brain enzyme called calcineurin may contribute to the development of schizophrenia, according to new research by scientists at The Rockefeller University, Massachusetts Institute of Technology...
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