The screening center at The Rockefeller University exists to aid researchers in their search for small molecule modulators of biological functions. The center currently has a library of just over 30,000 compounds and is continuously expanding. The screening room staff is trained in the use of multiple liquid handling robotic systems to allow the user more time to focus on data acquisition and analysis and less time worrying about assay execution. The center is currently configured for liquid handling in a 96 or 384 well format through the use of 96 tip liquid handling systems, pin tools and 8-channel systems for cherry picking. For detection, the center has available two multimode plate readers with one system capable of kinetic analysis. High content screening is also possible using the center's Discovery-1 automated microscope system.

Other services provided by the HTSRC include:

• Consultation on assay development.
• Assistance in validating the assay.
• Configuring the assay for high throughput screening.
• Additional assistance with data analysis and compound selection will be provided as needed.