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Welcome

Welcome to the Rockefeller University Genomics Resource Center!
The Genomics Resource Center at Rockefeller University was established in December 2004 by combining two previous resource centers, Gene Array and Genotyping. The Genomics Resource Center offers comprehensive services to support your research needs for genotyping and gene expression analysis.

Gene Expression Analysis:

  • Whole genome expression analysis based on Affymetrix GeneChips
  • Whole genome expression analysis based on Illumina BeadArrays
  • Alternative splicing analysis based on Affymetrix exon arrays
  • Novel transcript discovery based on Affymetrix tiling arrays
  • In-house custom cDNA and oligo array printing and processing
  • Real-time quantitative PCR for individual gene expression analysis

SNP Genotyping:

  • Whole genome SNP genotyping based on Affymetrix GeneChips
  • Whole genome SNP genotyping based on Illumina BeadArrays
  • Linkage analysis based on Illumina Human SNP linkage panel (5861 loci)
  • Linkage analysis and congenic strain construction based on Illumina Mouse SNP Low Density (377 loci) and Medium Density (1449 loci) panels
  • MHC region mapping based on Illumina MHC SNP panel (2360 loci)
  • Custom SNP genotyping at various multiplex levels (individual to 1536-plex)

Microsatellite Genotyping:

  • Marker-assisted mouse congenic stain construction with over 100 mouse microsatellite markers
  • Mouse genetic background checkup
  • Flexible fragment analysis with user provided markers
  • Identity testing with a panel of 15 highly polymorphic human microsatellite markers

DNA Methylation Analysis:

  • Based on Illumina GoldenGate Assays with both custom and standard cancer panels
  • Up to 1536 CpG sites can be analyzed simultaneously

Next-generation Sequencing:

  • Sequencing and resequencing
  • Digital gene expression
  • Small RNA discovery and quantification
  • DNA binding analysis (ChiP-Seq)