The Rockefeller UniversityLaboratory of Cellular and Structural Biology
Laboratory of Cellular and Structural Biology
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PUBLICATIONS
  1. M.P. Rout.
    "The peroxisome: a production in four acts." J Cell Biol. 181(2) (2008) 185-7.
  2. N.J. Moorman, I.M. Cristea, S.S. Terhune, M.P. Rout, B.T. Chait, T. Shenk.
    "Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex." Cell Host Microbe. 3(4) (2008) 253-62.
  3. L.F. Westblade, L. Minakhin, K. Kuznedelov, A.J. Tackett, E.J. Chang, R.A. Mooney, I. Vvedenskaya, Q. Wang, F.W. Studier, M.P. Rout, R. Landick, B.T. Chait, K. Severinov, S.A. Darst.
    "Rapid isolation and identification of T4 bacteriophage-encoded modifications of Escherichia coli RNA polymerase using immunoisolation and MALDI MS." J. Proteome Res. 7(3) (2008) 1244-50.
  4. F. Alber, S. Dokudovskaya, L.M. Veenhoff, W. Zhang, J. Kipper, D. Devos, A. Suprapto, O. Karni-Schmidt, R. Williams, B.T. Chait, M.P. Rout, A. Sali.
    "Determining the architectures of macromolecular assemblies." Nature 450 (2007) 683-694.
  5. F. Alber, S. Dokudovskaya, L.M. Veenhoff, W. Zhang, J. Kipper, D. Devos, A. Suprapto, O. Karni-Schmidt, R. Williams, B.T. Chait, A. Sali, M.P. Rout.
    "The molecular architecture of the nuclear pore complex." Nature 450 (2007) 695-701.
  6. M. Oeffinger, K.E. Wei, R. Rogers, J.A. Degrasse, B.T. Chait, J.D. Aitchison, M.P. Rout.
    "Comprehensive analysis of diverse ribonucleoprotein complexes." Nat Methods. (11) (2007) 951-6.
  7. J. Zhang, P. Harnpicharnchai, J. Jakovljevic, L. Tang, Y. Guo, M. Oeffinger, M.P. Rout, S.L. Hiley, T. Hughes, J.L. Woolford, Jr.
    "Assembly factors Rpf2 and Rrs1 recruit 5S rRNA and ribosomal proteins rpL5 and rpL11 into nascent ribosomes." Genes Dev. 21(20) (2007) 2580-92.
  8. A. Zilman, S. Di Talia, B.T. Chait, M.P. Rout, M.O. Magnasco.
    "Efficiency, Selectivity, and Robustness of Nucleocytoplasmic Transport." PLoS Comput Biol. 3(7) (2007) e125.
  9. M. Oeffinger, A. Fatica, M.P. Rout, D. Tollervey.
    "Yeast Rrp14p is required for ribosomal subunit synthesis and for correct positioning of the mitotic spindle during mitosis." Nucleic Acids Res. 35(4) (2007) 1354-66.
  10. B.L. Timney, J. Tetenbaum-Novatt, D.S. Agate, R. Williams, W. Zhang, B.T. Chait, M.P. Rout.
    "Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo." J Cell Biol. 175(4) (2006) 579-93.
  11. D.M. Leslie, B. Timney, M.P. Rout, J.D. Aitchison.
    "Studying nuclear protein import in yeast." Methods 39(4) (2006) 291-308.
  12. Q.J. Wang, Y. Ding, S. Kohtz, N. Mizushima, I.M. Cristea, M.P. Rout, B.T. Chait, Y. Zhong, N. Heintz, Z. Yue.
    "Induction of autophagy in axonal dystrophy and degeneration." J Neurosci. 26(31) (2006) 8057-68.
  13. I.M. Cristea, J.W. Carroll, M.P. Rout, C.M. Rice, B.T. Chait, M.R. Macdonald.
    "Tracking and elucidating alphavirus-host protein interactions." J Biol Chem.281(40) (2006) 30269-78.
  14. S. Dokudovskaya, R. Williams, D. Devos, A. Sali, B.T. Chait, M.P. Rout.
    "Protease Accessibility Laddering: a proteomic tool for probing protein structure." Structure 14(4) (2006) 653-60.
  15. D. Devos, S. Dokudovskaya, R. Williams, F. Alber, N. Eswar, B.T. Chait, M.P. Rout, A. Sali.
    "Simple fold composition and modular architecture of the nuclear pore complex." Proc. Natl. Acad. Sci. USA 103(7) (2006) 2172-7.
  16. C. Strambio-de-Castillia, J. Tetenbaum-Novatt, B.S. Imai, B.T. Chait, M.P. Rout.
    "A Method for the Rapid and Efficient Elution of Native Affinity-Purified Protein A Tagged Complexes." J Proteome Res. 4(6) (2005) 2250-6.
  17. I.M. Cristea, R. Williams, B.T. Chait, M.P. Rout.
    "Fluorescent proteins as proteomic probes." Mol Cell Proteomics. 4(12) (2005) 1933-194.
  18. A.J. Tackett, J.A. DeGrasse, M.D. Sekedat, M. Oeffinger, M.P. Rout, B.T. Chait.
    "I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions." J Proteome Res. 4(5) (2005) 1752-6.
  19. A.J. Tackett, D.J. Dilworth, M.J. Davey, M. O'Donnell, J.D. Aitchison, M.P. Rout, B.T. Chait.
    "Proteomic and genomic characterization of chromatin complexes at a boundary." J Cell Biol. 169(1) (2005) 35-47.
  20. M. Niepel, C. Strambio-de-Castillia, J. Fasolo, B.T. Chait, M.P. Rout.
    "The nuclear pore Complex-associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assembly." J Cell Biol. 170(2) (2005) 225-35.
  21. D. Devos, S. Dokudovskaya, F. Alber, R. Williams, B.T. Chait, A. Sali, M.P. Rout.
    "Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture." PLoS Biology 2 (12) (2004) e380.
  22. D.M. Leslie, W. Zhang, B.L. Timney, B.T. Chait, M.P. Rout, R.W. Wozniak, J.D. Aitchison.
    "Characterization of karyopherin cargoes reveals unique mechanisms of kap121p-mediated nuclear import." Mol Cell Biol. 24 (19) (2004) 8487-503.
  23. V. Archambault, E.J. Chang, B.J. Drapkin, F.R. Cross, B.T. Chait, M.P. Rout.
    "Targeted proteomic study of the Cyclin-Cdk module." Mol. Cell 14(6) (2004) 699-711.
  24. B.L. Timney and M.P. Rout.
    "Robbing from the pore." Nat. Cell Biol. 6 (2004) 177-9.
  25. M.P. Rout, J.D. Aitchison, M.O. Magnasco and B.T. Chait.
    "Virtual gating and nuclear transport: the hole picture." Trends Cell Biol. 13 (2003) 622-8.
  26. V. Archambault, C.X. Li, A.J. Tackett, R. Wäsch, B.T. Chait, M.P. Rout, F.R. Cross.
    "Genetic and biochemical evaluation of the importance of Cdc6 in regulating mitotic exit." Mol. Biol. Cell 14 (2003) 4592-604.
  27. D.M. Leslie, B. Grill, M.P. Rout, R.W. Wozniak, J.D. Aitchison.
    "Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast." Mol. Cell. Biol. 8 (2002) 2544-55.
  28. J.D. Aitchison and M.P. Rout.
    "A tense time for the nuclear envelope." Cell 108 (2002) 301-304.
  29. S. Dokudovskaya, L.M. Veenhoff, M.P. Rout.
    "Cleave to leave: structural insights into the dynamic organization of the nuclear pore complex." Mol Cell. 10(2): (2002) 221-3.
  30. J. Kipper, C. Strambio-de-Castillia, A. Suprapto, M.P. Rout.
    "Isolation of nuclear envelope from Saccharomyces cerevisiae." Methods Enzymol. 351 (2002) 394-408.
  31. C. Strambio-de-Castillia, M.P. Rout.
    "The structure and composition of the yeast NPC." Results Probl Cell Differ. 35 (2002) 1-23.
  32. M.P. Rout and M.C. Field.
    "Isolation and characterisation of subnuclear compartments from Trypanosoma brucei: identification of a major repetitive nuclear lamina component." J. Biol. Chem. 276 (2001) 38261-38271.
  33. P. Harnipicharnchai, J. Jakovljevic, E. Horsey, T. Miles, J. Roman, M. Rout, D. Meagher, B. Imai, Y. Guo, C. J. Brame, J. Shabanowitz, D. F. Hunt, J. L. Woolford, Jr.
    "Composition and Functional Characterization of Yeast 66S Ribosome Assembly Intermediates." Mol. Cell 8 (2001) 505-515.
  34. J.D. Aitchison and M.P. Rout.
    "The Nuclear Envelope and Nucleocytoplasmic Transport." In: The Encyclopedia of Genetics, Harcourt Press. (2001).
  35. D. J. Dilworth, A. Suprapto, J. C. Padovan, B.T. Chait, R.W. Wozniak, M.P. Rout and J.D. Aitchison.
    "Nup2p Dynamically Associates with the Distal Regions of the Yeast Nuclear Pore Complex." J. Cell Biol. 153 (2001) 1465-1478.
  36. J.D. Aitchison, M.P. Rout.
    "The nuclear pore complex as a transport machine." J Biol Chem. 276(20) (2001) 16593-6.
  37. J.D. Aitchison and M.P. Rout
    "The Road to Ribosomes: Filling Potholes in the Export Pathway." J. Cell Biol. 151 (2000) 23-26.
  38. M.P. Rout, J.D. Aitchison, A. Suprapto, K. Hjertaas, Y. Zhao and B.T. Chait.
    "The yeast nuclear pore complex: composition, architecture and mechanism." J. Cell. Biol. 148 (2000) 635-652.
  39. M.P. Rout, and J.D. Aitchison,
    "Pore Relations: Nuclear Pore Complexes and Nucleocytoplasmic Exchange." Essays in Biochemistry 36 (2000) 79-85.
  40. C. Strambio-de-Castillia, G. Blobel and M.P. Rout.
    "Proteins Connecting the Nuclear Pore Complex with the Nuclear Interior." J. Cell Biol. 144 (1999) 839-850.
  41. C. Strambio-de-Castillia and M.P. Rout.
    "TAPping into transport." Nat Cell Biol. 1:E3 (1999) 1-3.
  42. Q. Yang, M.P. Rout and C.W. Akey.
    "Three-Dimensional Architecture of the Isolated Yeast Nuclear Pore Complex: Functional and Evolutionary Implications." Mol. Cell, 1 (1998) 223-234.
  43. M.P. Rout and J.V. Kilmartin.
    "Preparation of Yeast Spindle Pole Bodies" Cell Biology : A Laboratory Handbook, vol. 2, 120-128 (1998), 2nd Edition.
  44. M.P. Rout and C. Strambio-de-Castillia.
    "Isolation of Yeast Nuclear Pore Complexes and Nuclear Envelopes" Cell Biology : A Laboratory Handbook, vol. 2, 143-152 (1998), 2nd Edition.
  45. R.W. Wozniak, M.P. Rout and J.D. Aitchison.
    "Karyopherins and Kissing Cousins." Trends Cell Biol. 8 (1998) 184-188.
  46. H. Chial, M.P. Rout, T. H. Giddings, Jr. , and M. Winey.
    "Saccharomyces cerevisiae Ndc1p is a Shared Component of Nuclear Pore Complexes and Spindle Pole Bodies" J. Cell Biol. 143 (1998) 1789-1800.
  47. M.P. Rout, G. Blobel and J.D. Aitchison.
    "A Distinct Nuclear Import Pathway Used by Ribosomal Proteins." Cell, 89 (1997) 715-725.
  48. E. Bullitt, M.P. Rout, J.V. Kilmartin and C.W. Akey.
    "The Yeast Spindle Pole Body Is Assembled around a Central Crystal of Spc42p." Cell, 89 (1997) 1077-1086.
  49. U. Nehrbass, M.P. Rout, S. Maguire, G. Blobel and R.W. Wozniak.
    "Nup188p, a Novel Yeast Nucleoporin, Is Part of a Functionally Interacting Group of Major Nuclear Pore Complex Constituents." J. Cell Biol. 133 (1996) 1153-1162.
  50. J.D. Aitchison, G. Blobel and M.P. Rout.
    "KAP104: A Novel Yeast Karyopherin that Imports hnRNP Proteins into the Nucleus." Science, 274 (1996) 624-627.
  51. L.F. Pemberton, M.P. Rout and G. Blobel.
    "Disruption of the Nucleoporin Gene NUP133 Results in Clustering of Nuclear Pore Complexes." Proc. Natl. Acad. Sci. USA 92 (1995) 1187-1191.
  52. D.M. Kraemer, C. Strambio-de-Castillia, G. Blobel and M.P. Rout.
    "The Essential Yeast Nucleoporin NUP159 Is Located on the Cytoplasmic Side of the Nuclear Pore Complex and Serves in Karyopherin-mediated Binding of Transport Substrate." J. Biol. Chem. 270 (1995) 19017-19021.
  53. C. Strambio-de-Castillia, G. Blobel and M.P. Rout.
    "Isolation and Characterization of the Yeast Nuclear Envelope." J. Cell Biol. 131 (1995) 19-31.
  54. J.D. Aitchison, M.P. Rout, M. Marelli, G. Blobel and R.W. Wozniak.
    "Two Novel Related Yeast Nucleoporins Nup170p and Nup157p: Complementation with the Vertebrate Homologue Nup155p and Functional Interactions with the Yeast Nuclear Pore-Membrane Protein Pom152p." J. Cell Biol. 131 (1995) 1133-1148.
  55. J.D. Aitchison, G. Blobel and M.P. Rout.
    "Nup120p: A Yeast Nucleoporin Required for NPC Distribution and mRNA Transport." J. Cell Biol. 131 (1995) 1659-1675.
  56. R.W. Wozniak, G. Blobel and M.P. Rout.
    "POM152 is an Integral Protein of the Pore Membrane Domain of the Yeast Nuclear Envelope." J. Cell Biol. 125 (1994) 31-42.
  57. M.P. Rout and S.R. Wente.
    "Pores for Thought: Nuclear Pore Complex Proteins." Trends Cell Biol. 4 (1994) 357-365.
  58. M.P. Rout and J.V. Kilmartin.
    "Preparation of Yeast Spindle Pole Bodies." Cell Biology: A Laboratory Handbook, vol. 1, (1994) 605-612
  59. M.P. Rout and G. Blobel.
    "Isolation of the Yeast Nuclear Pore Complex." J. Cell Biol. 123 (1993) 771-783.
  60. S.R. Wente, M.P. Rout and G. Blobel.
    "A New Family of Yeast Nuclear Pore Complex Proteins." J. Cell Biol. 119 (1992) 705-723.
  61. M.P. Rout and J.V. Kilmartin.
    "Yeast Spindle Pole Body Components." CSH Symp. Quant. Biol. LVI (1991) 687-692.
  62. M.P. Rout and J.V. Kilmartin.
    "Components of the Yeast Spindle and Spindle Pole Body." J. Cell Biol. 111 (1990) 1913-1927.
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