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Postdoctoral position Epigenetic control of B cell differentiation and myelomagenesis

The Laboratory of Immune Cell Epigenetics and Signaling at The Rockefeller University, New York, NY is searching for an outstanding postdoctoral researcher interested in studying the epigenetic control of B cell differentiation and myelomagenesis.  The project will investigate the role of methyltransferase MMSET/NSD1 in transcriptional control of early B cell differentiation, primordial lymphopoiesis and malignant transformation of plasma lineage cells. The project will utilize mouse mutants with conditional inactivation or overexpression of MMSET that are readily available for the studies. The postdoctoral researcher will play a key role in our effort to understand rules that govern transcriptional diversification of primordial and adult B cell lymphopoiesis, including immunoglobulin gene rearrangement and B cell survival. Candidates must have a strong background in B cell immunology and mouse genetics, and familiarity with basic principles of gene regulation.  Applicants with strong quantitative skills are particularly encouraged to apply. Interested candidates should send their curriculum vitae; and a description of their scientific interest including the names and contact information of three professional references to labriom@rockefeller.edu.  Please include in the Subject Line:  Application for Postdoctoral Opportunity – Epigenetic control of B cell differentiation and myelomagenesis.

The position is available immediately.Applications will be accepted until the position is filled. The position is available immediately.