Researchers studying two forms of skin cancer identified a long-overlooked factor determining why some tumors are more likely to metastasize than others: the physical properties of the tissue in which the cancer originates. The findings might set the stage for new ways to monitor and treat the diseases.
Two studies from Jean-Laurent Casanova reveal that in a significant minority of patients with serious COVID-19, the interferon response has been crippled by genetic flaws or by rogue antibodies that attack interferon itself.
The Wall Street Journal
“The immune system in people is as diverse as beauty, height, intelligence and any other human feature,” said molecular immunologist Michel Nussenzweig at Rockefeller University in New York. “Not everybody is the same in their ability to fight infection.”
Clinical use of heritable genome editing should not be considered until it's established that precise genomic changes can be made reliably without introducing undesired changes, according to a joint NAS, NAM, and Royal Society commission co-chaired by Rockefeller president Richard P. Lifton.