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Researchers use new CRISPR-based strategy to replicate disease in cells

To explore in detail how specific genetic errors can lead to disease, scientists need to perform experiments in cells that carry these exact mutations. Now, the ability to create these cellular replicas using new genome editing technology has been facilitated thanks to work by Rockefeller Univers...

A central clock runs the cell division cycle

Each time a cell divides, it replicates its DNA once, then separates the two copies from each other and splits into two daughter cells. The event is intricately coordinated and was long known to be under the influence of cyclins—an aptly named group of proteins whose levels go up and down as the ...

New method allows first look at key stage of human development, embryo implantation

Accompanying commentary recommends revisiting current bioethical guidelines in light of advance       Despite significant biomedical advances in recent decades, the very earliest events of human development­—those that occur during a critical window just after fertilization—h...

In the News - Wall Street Journal - Brivanlou

Scientists Grow Embryos for Up to 13 Days Outside the Uterus   "In addition, to both teams’ surprise, the embryos outside the womb were able to 'self-organize' or begin to set in motion early development of key body organs without any biological cues from the mother. 'That is counterintuitive to ...