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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
Displaying 87 of 2735 articles.

Researchers create map of “shortcuts” between all human genes

...Giles lab, headed by Jean-Laurent Casanova, previously showed that children with HSE have mutations in TLR3 or in genes that are closely functionally related to TLR3. In other words, these genes are located at a short biological distance from TLR3. As a result, novel herpe...

Nature Immunology: December 25, 2011

...Diaz, J Magarian Blander, Claire-Michèle Farber, Guido Silvestri, Charlotte Cunningham-Rundles, Michaela Calvillo, Carlo Dufour, Lucia Dora Notarangelo, Vassilios Lougaris, Alessandro Plebani, Jean-Laurent Casanova, Stephanie C. Ganal, Andreas Diefenbach, Juan Ignacio Arós...

Scientists pinpoint source of recurrent yeast infections in autoimmune syndrome

...In 33 patients with the ailment, known as autoimmune polyendocrine syndrome, or APS-1, researchers led by Jean-Laurent Casanova, head of the Laboratory of Human Genetics of Infectious Diseases, found antibodies that attack a class of immune proteins called cytokines. Altho...

Brain displays an intrinsic mechanism for fighting infection

...The lab, headed by Jean-Laurent Casanova, collaborated with scientists at Harvard Medical School and Memorial Sloan-Kettering Cancer Institute to create induced pluripotent stem cells. Made from the patients’ own tissue, the stem cells were developed into central nervous s...

Milestones

...Jean-Laurent Casanova, a 2014 Sanofi-Institut Pasteur Award, recognizing scientific progress in the life sciences. Dr. Casanova is being honored for his discovery of the role of single-gene mutations in infectious diseases, leading to novel treatments for certain pe...

Protein proves vital in immune response to bacteria

...But the lab, headed by Senior Attending Physician Jean-Laurent Casanova, tapped into their database of 300 people with what’s known as Mendelian susceptibility to mycobacterial disease, a rare disorder that predisposes individuals to become severely ill from exposure to my...

Nature Genetics: December 11, 2011

Nature Genetics online: December 11, 2011 Mutations at a single codon in Mad homology 2 domain of SMAD4 cause Myhre syndrome Carine Le Goff, Clémentine Mahaut, Avinash Abhyankar, Wilfried Le Goff, Valérie Serre, Alexandra Afenjar, Anne Destrée, Maja di Rocco, Delphine Héron, Sébastien Jacquemon...

Milestones

...Jean-Laurent Casanova, the Presidential Award from the Clinical Immunology Society. Dr. Casanova researches the genetic basis of pediatric infectious diseases and is head of the St. Giles Laboratory of Human Genetics of Infectious Diseases and a Howard Hughes Medica...

Genetic epidemiologist named visiting professor

ZACH VEILLEUX Laurent Abel, a geneticist interested in infectious diseases, has been appointed a visiting professor and member of Jean-Laurent Casanova’s Laboratory of Human Genetics of Infectious Disease. Though he will continue to be based in France — his existing la...

Charles M. Rice awarded Dautrebande Prize

...Jean-Laurent Casanova, senior attending physician at The Rockefeller University Hospital and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases received the award in 2004 while at the Necker Medical School in Paris.