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In the News – NPR – Casanova

...The response to influenza is genetically impaired,' says [Jean-Laurent] Casanova. He's hoping that the study will catch the interest of other pediatricians and lead to more patients offering their genomes for further research."

Researchers uncover molecular mechanisms of rare skin disease

...Led by Rockefeller scientist Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, a group of researchers recently elucidated the molecular mechanisms that make people with EV vulnerable to ß-HPVs. In a new study, published in the Journal of Experimental ...

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Genetic mutation identified as culprit in rare infectious disease

...In an article published in eLife, Jean-Laurent Casanova has uncovered the human genetics factors that make these outliers susceptible to infection. His team suspected that Whipple’s is the latest in a growing number of genetic defects that increases people’s vulnerability to specific microbes. T...

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In brief: Mutation explains why some people are more vulnerable to viral brain infection

...Rockefeller’s Jean-Laurent Casanova has identified mutations in a single gene that may explain what goes wrong in cases of encephalitis of the brain stem, the part of the brain that controls many basic functions including heart rate and breathing. Shen-Ying Zhang, assistant professor of clinical i...

Jeffrey V. Ravetch to receive 2018 Robert Koch Award

...Rice in 2015 for studies of the hepatitis C virus, Jean-Laurent Casanova in 2014 for work on genetic susceptibility to infectious disease, and Ralph Steinman in 1999 for discovering dendritic cells and their influence on immunity. René Jules Dubos was the first Rockefeller recipient of the prize...

Michel C. Nussenzweig wins 2017 Sanofi-Institut Pasteur Award

...Ravetch in 2012 and Jean-Laurent Casanova in 2014.

Immunity 39: 676-686 (10-17-13)

Immunity 39: 676-686 An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis Bertrand Boissonsend, Chenhui Wang, Vincent Pedergnana, Ling Wu, Sophie Cypowyj, Michel Rybojad, Aziz Belkadi, Capucine Picard, Laurent Abel, Claire Fieschi, Anne Pue...

Talking Science lecture introduces students to the genetic aspects of infectious diseases

As he opened this year’s Talking Science lecture, geneticist Jean-Laurent Casanova made a stark observation to his teenage audience: “If we had been here 150 years ago, about half of you would already have died.” The primary reason, he told the 350 high school students and 60 teachers present,...

The Lancet 379: 2500 (June 30, 2012)

The Lancet 379: 2500 Herpes in STAT1 deficiency Beáta Tóth, Leonóra Méhes, Szilvia Taskó, Zsuzsanna Szalai, Zsolt  Tulassay, Sophie Cypowyj, Jean-Laurent Casanova, Anne Puel and László Maródi

New research explains why a common bacterium can produce severe illness

...Jean-Laurent Casanova, head of St. Giles Laboratory of Human Genetics of Infectious Diseases and Howard Hughes Medical Institute Investigator, led a team of researchers to uncover how two different conditions—a genetic immunodeficiency and delayed acquired immunity—can combine to produce a life-...

Recent Awards and Honors

Gabriel Victora named recipient of an NIH Director’s Pioneer Award

Gabriel Victora named recipient of an NIH Director’s Pioneer Award

October 2, 2018

Victora, head of the Laboratory of Lymphocyte Dynamics, received this grant to expand his novel method that makes it possible to monitor physical interactions between cells.

hixin Liu and Jeremy Rock have each received NIH Director’s New Innovator Awards

Shixin Liu and Jeremy Rock have each received NIH Director’s New Innovator Awards

October 2, 2018

Liu, head of the Laboratory of Nanoscale Biophysics and Biochemistry, and Rock, head of the Laboratory of Host-Pathogen Biology, received grants that are part of the NIH’s High-Risk, High-Reward Research Program.

More awards and honors

Rockefeller in the News

Harper's Magazine

Jeffrey Friedman examines how World War I delayed a treatment for diabetes and derailed one man’s chance at immortality.

Science

"Error-free genomes from a broad sampling of vertebrates will enable researchers 'to address questions not possible to [answer] before,' adds neuroscientist Erich Jarvis of The Rockefeller University in New York City, who leads G10K."

New York Times

By looking at which genes are activated in the brains of queens and workers of different ant species, Dr. [Daniel] Kronauer and his colleagues determined that a hormone called insulin-peptide 2, or ILP2, played the most important role.

 

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Communications and Public Affairs

The Office of Communications and Public Affairs promotes and disseminates research news and other information about The Rockefeller University.