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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
Displaying 87 of 2735 articles.

The genetic underpinnings of severe staph infections

...Rockefeller immunologist Jean-Laurent Casanova examined the protein-coding genomes of more than 100 patients who had suffered from unexplained severe staph infections. The common genetic thread linking some of th...

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Missing immune molecule may explain why some HPV patients sprout giant horn-like growths

...How could one virus provoke such a severe reaction in a select few, but leave most people symptom-free? In a new study published in Cell, Rockefeller’s Jean-Laurent Casanova answers this question by examining the genetics of an otherwise healthy patient who contracted a se...

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The common thread in severe COVID-19 

...Two papers from the laboratory of Jean-Laurent Casanova previously demonstrated that at least 10 percent of severe cases can be chalked up to either a genetic condition that cripples IFN production, or misguided antibodies that attack those crucial proteins. Now, two new s...

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How one patient’s rare mutation helped solve a mycobacterial mystery

...The lab of Jean-Laurent Casanova, which has spent 25 years studying the interplay between human genes and mycobacterial disease, continues to uncover the genetic defects that separate those who develop serious infections from those who remain symptomless after being expose...

Jean-Laurent Casanova receives the 2016 Inserm Grand Prix

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, has won the 2016 Inserm Grand Prix for his work on the genetic basis of infectious diseases. The prestigious award, given annually by Inserm—the French National Ins...

Jean-Laurent Casanova honored with the Korsmeyer Award

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, is the recipient of the 2016 Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award, given by the Ameri...

Jean-Laurent Casanova elected to the National Academy of Medicine

Jean-Laurent Casanova, who investigates genetic vulnerability to infectious diseases among children, has been elected to the U.S. National Academy of Medicine, the health and medicine arm of the National Academy of Sciences. Casanova is professor and head of the St. Gi...

Rockefeller scientists investigate life-threatening inflammation affecting children with COVID-19

...We may find a genetic clue that could help explain what is driving this severe complication in these children, which can in turn inform their clinical care,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockef...

Scientists trace severe COVID-19 to faulty genes and autoimmune condition

...These findings provide compelling evidence that the disruption of type I interferon is often the cause of life-threatening COVID-19,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University and a H...

Leslie Vosshall and Jean-Laurent Casanova elected to the National Academy of Sciences

...Vosshall, Robin Chemers Neustein Professor and head of the Laboratory of Neurogenetics and Behavior, has been named a member, and Jean-Laurent Casanova, senior attending physician, professor, and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, ha...
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