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Displaying 92 of 2850 articles.

Jeffrey V. Ravetch to receive 2018 Robert Koch Award

...Rice in 2015 for studies of the hepatitis C virus, Jean-Laurent Casanova in 2014 for work on genetic susceptibility to infectious disease, and Ralph Steinman in 1999 for discovering dendritic cells and their influence on immunity. René Jules Dubos was the first Rockefeller recipi...

Scientists trace severe COVID-19 to faulty genes and autoimmune condition

...These findings provide compelling evidence that the disruption of type I interferon is often the cause of life-threatening COVID-19,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University and a Howard H...

Jean-Laurent Casanova honored with Belgium’s highest scientific prize

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at Rockefeller University, has received the 2011 InBev-Baillet Latour Health Prize for his pioneering work on the identification of genes that predispose for human infectio...

Patient with unusually severe infection leads scientists to a rare type of immune deficiency

...An unexpected life-threatening infectious disease that is not explained by a compromised immune system often turns out to be a genetic disorder,” says lead investigator Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at Rockefeller...

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Researchers find genetic link to tuberculosis

...Now, Rockefeller scientist Jean-Laurent Casanova has identified a genetic condition that makes the immune system susceptible to mycobacterial attack. Last year, Casanova showed that the risk of developing TB is heightened in people who have two copies of a particular varia...

Llamas immune to coronavirus, what zebrafish are thinking, and other memorable science stories of 2020 

...Shortly thereafter, Jean-Laurent Casanova and colleagues made headlines with two reports revealing that people with the most severe cases of the disease frequently lack interferon I, a cluster of proteins that repel viruses, providing the first molecular explanation for why some ...

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In brief: Mutation explains why some people are more vulnerable to viral brain infection

...Rockefeller’s Jean-Laurent Casanova has identified mutations in a single gene that may explain what goes wrong in cases of encephalitis of the brain stem, the part of the brain that controls many basic functions including heart rate and breathing. Shen-Ying Zhang, assistant profe...

Milestones

...Jean-Laurent Casanova, the 2011 InBev-Baillet Latour Health Prize, Beligum’s highest scientific honor. With a value of 250,000 euros, the InBev-Baillet prize recognizes the practical application of basic research; Dr. Casanova is honored for his work on the identification ...

Study pinpoints rare genetic change that may boost risk of HPV-related illness

...We’ve cracked the enigma of why the boys developed these warts,” says lead investigator Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases. The findings add to a growing body of evidence that is changing how researchers think about in...

In the News - Newsweek - Casanova

...Jean-Laurent Casanova, a professor at Rockefeller University who studies how genetic coding can make a person more susceptible to disease. 'If we continue to rely solely on antibiotics, we are going to have a problem.'"