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A first look at the earliest decisions that shape a human embryo

For the first time, scientists have shown that a small cluster of cells in the human embryo dictates the fate of other embryonic cells. The discovery of this developmental “organizer” could advance research into many human diseases, and it suggests we have more in common with birds than meets the eye.

Gaby Maimon and Luciano Marraffini are named HHMI investigators

Maimon, who studies cognition and decision-making, and Marraffini, who studies the bacterial defense system CRISPR-Cas, are among 19 scientists nationwide to receive this designation.

Sohail Tavazoie promoted to professor

Sohail Tavazoie, a physician-scientist who studies the genes that regulate a tumor’s ability to metastasize, has been promoted to professor.

Rockefeller takes first place in global ranking of scientific impact

Out of over 900 universities from 55 different countries, Rockefeller tops a survey measuring the impact of university research publications, scoring the highest percentage of frequently cited scientific publications.

A new way to watch brain activity in action

A new imaging tool makes it possible to track the firing of millions of brain cells in mice while the animals move about as normal. The method could help shed new light onto the neural processes that create behavior.

Jeffrey V. Ravetch to receive 2018 Robert Koch Award

Ravetch receives the award for his groundbreaking work analyzing the immune system’s antibody response. He has worked for decades on the Fc fragment of the antibody molecule and its binding partners, known as Fc receptors.

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New method allows scientists to study how HIV persists

Scientists have developed a new strategy to study the cells that host hidden reserves of dormant HIV, a step that may lead to new treatments that go beyond controlling the infection and instead aim to eradicate the virus entirely.

Small molecule from Kapoor lab is accepted as first Bridge Medicines drug candidate

A chemical inhibitor targeting basal cell carcinoma, originating from Tarun Kapoor’s lab, is graduating from the Tri-Institutional Therapeutics Discovery Institute into Bridge Medicines.

From infection-dodging stem cells, new tactics for research on viral disease

Among other superpowers, stem cells have a knack for fending off viruses like dengue and zika. Scientists have gained new insight into these curious defense strategies—knowledge they say could fuel the development of drugs against a range of diseases.

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Structural studies help explain how cancer cells resist chemotherapy

New research sheds light on how some cancer cells use molecular pumps to expel chemotherapy drugs before they have a chance to work.

Recent Awards and Honors

Distinguished Teaching Award Plaque

Seth A. Darst and Michael P. Rout receive Distinguished Teaching Awards

June 14, 2018

Darst and Rout were honored at the 2018 Convocation luncheon for their dedication to training Rockefeller graduate students. Together, they teach a course in biochemistry and biophysics methods.

Gregory M. Alushin

Gregory M. Alushin honored as a 2018 Pew Scholar

June 14, 2018

Alushin has been named a biomedical science scholar for his investigation of how cells sense and respond to mechanical force.

Rockefeller in the News

Scientific American

As [A. James] Hudspeth explored the neural mechanisms of hearing over the years, he developed a special appreciation for the intricate anatomy of the inner ear—an appreciation that transcends the laboratory. “I think we as scientists tend to underemphasize the aesthetic aspect of science,” he says.

Science

"'It is mind-blowing' that cells from such evolutionarily distant species can share these developmental instructions, says Ali Brivanlou, a stem cell biologist at The Rockefeller University in New York City and a senior author on the new study. The organizer 'has been conserved evolutionarily over hundreds of millions of years, so not seeing it would have been a surprise,' he says. But, 'There is something really emotional about looking that far back at human origin.'"

NIH Director's Blog

"[Michael] Rout and [Brian] Chait have spent more than 20 years trying to solve the structure of NPCs. Not only are NPCs large and constantly engaged in shuttling molecules in and out, they also represent moving machines."

 

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Communications and Public Affairs

The Office of Communications and Public Affairs promotes and disseminates research news and other information about The Rockefeller University.