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Small molecule from Kapoor lab is accepted as first Bridge Medicines drug candidate

A chemical inhibitor targeting basal cell carcinoma, originating from Tarun Kapoor’s lab, is graduating from the Tri-Institutional Therapeutics Discovery Institute into Bridge Medicines.

From infection-dodging stem cells, new tactics for research on viral disease

Among other superpowers, stem cells have a knack for fending off viruses like dengue and zika. Scientists have gained new insight into these curious defense strategies—knowledge they say could fuel the development of drugs against a range of diseases.

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Structural studies help explain how cancer cells resist chemotherapy

New research sheds light on how some cancer cells use molecular pumps to expel chemotherapy drugs before they have a chance to work.

Astrophysicist Kip Thorne to receive Rockefeller’s 2018 science writing prize

Thorne is recognized for his deft explanations that have drawn readers into the space-, time-, and mind-bending realm of Einstein’s ideas. The prize, which honors scientists as inspirational authors, will be presented on April 17.

What happens to a dying cell’s corpse? New findings illuminate an old problem

Scientists have discovered a curious way for cells to die. In studying it, they are learning about how remnants of diseased cells are normally chewed up and removed.

Scientists map the portal to the cell’s nucleus

The gateway to cellular headquarters has 552 components. A new map that shows how all these pieces fit together could help scientists study numerous diseases.

Scientists caution that a rare childhood liver cancer can spread to the brain

A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver.

Molecular doorstop could be key to new tuberculosis drugs

In discovering how an antibiotic kills the bacteria that cause tuberculosis, scientists open the door to new treatments for the disease—and possibly others, as well.

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Building the machinery that makes proteins

Scientists have used cryo-electron microscopy to capture the very first snapshots of the large ribosomal subunit—part of the ribosome responsible for forging bonds between amino acids, the building blocks of proteins—coming together.

Molecule discovered in dirt could help against multi-resistant bacteria

In mining soil for natural drugs, scientists have discovered a brand-new antibiotic potent against many bacteria. They hope it could be used to treat infections that cannot be stopped with existing drugs.

Recent Awards and Honors

Priya Rajasethupathy to receive Presidential Early Career Award for Scientists and Engineers

July 2, 2019

Rajasethupathy is honored for her investigation of memory and related cognitive processes.

Li Zhao portrait

Li Zhao announced as 2019 Rita Allen Foundation Scholar

July 1, 2019

Zhao receives the award for her research on the origin and evolution of novel genes.

More awards and honors

Rockefeller in the News

NPR

"I really feel like I'm looking at one of the most mysterious aspect of our own existence," Brivanlou says. Brivanlou, Simunovic and their colleagues hope their creations will lead to fundamental discoveries that could have many implications, including a better understanding of the the origins of many diseases.

The New York Times

“It’s tempting to think marijuana is a harmless substance that poses no threat to teens and young adults. The medical facts, however, reveal a different reality.” —Mary Jeanne Kreek in an op-ed for The New York Times

Quanta Magazine

“We’re proposing that in fact, for much of eukaryotic evolution, the nucleus as we know it today didn’t exist,” said Michael Rout, a cell biologist at the Rockefeller University and one of the paper’s co-authors.

Seek magazine

Rockefeller’s flagship publication is interested not just in scientific results, but in the people, ideas, and conversations that ignite discovery. The latest issue looks deep into the brains of small critters and their decision-making processes. Also: how research on rare diseases could benefit us all, and much more.


From this issue

 

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