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Unlocking how the new Alzheimer’s drug lecanemab works

As with many cutting-edge therapies, we know more about the drug's effectiveness than we do about how it actually operates. A new study reveals a possible mechanism for its impact on patients.

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Boosters are key to protecting pregnant individuals and newborns against the worst effects of COVID

Patients with a specific cocktail of COVID exposure had the highest level of antibodies against SARS-CoV-2 and its variants, which also provided a strong immunological shield for their babies.

Researchers find an epigenetic key that unlocks common deadly cancers

In skin, some aberrant adult epidermal stem cells turn on SOX9, kickstarting a process that ultimately activates cancer genes.

An immune flaw may cause West Nile virus’s deadliest symptoms

With 40% of encephalitis cases now explained by an autoimmune deficiency, West Nile virus "is by far the best understood human infectious disease in the world. It’s stunning.”

How one of nature's most fundamental molecules forms

New high-resolution images of the large ribosomal subunit shed light on how human ribosomes are assembled.

Researchers discover neuronal mechanism linked to a minutes-long decision process in fruit flies

They identified a brain signal that guides one type of decision-making—findings that could build a foundation for understanding how humans make educated and strategic decisions.

The potential molecular indicators of Parkinson’s symptoms

Overlapping RNA changes in the blood and brain were associated with many of the clinical signs of the disease.

Proteome of rare liver cancer sheds new light on basic biology

Fibrolamellar carcinoma not only hinders the body's ammonia consumption but also produces ammonia, a finding with sweeping implications for treating this cancer—and the study of ammonia metabolism.

World’s first transgenic ants reveal how colonies respond to an alarm

The findings raise tantalizing possibilities for revealing what hundreds of ant odorant receptors are up to.

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New algorithm cleans microbiome data with unprecedented efficiency

The algorithm, dubbed SCRuB, can distinguish native bacteria and viruses from contaminants—a powerful tool for researchers working with the microbiome.