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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
Displaying 164 of 2761 articles.

Scientists prove how genetics change behavior by studying worms’ foraging strategies

“Organisms pay attention to what other members of their species are doing,” says Cori Bargmann, a neuroscientist at Rockefeller University. “It’s a very robust phenomenon that you see from humans on Twitter to bacteria, and everything in between.” That’s why Bargmann, Torsten N. W...

Researchers watch in 3D as neurons talk to each other in a living mouse brain

No single neuron produces a thought or a behavior; anything the brain accomplishes is a vast collaborative effort between cells. When at work, neurons talk rapidly to one another, forming networks as they communicate. Researchers led by Rockefeller University’s Alipasha Vaziri are developing tech...

Winrich Freiwald wins Columbia University’s 2016 W. Alden Spencer Award

Winrich Freiwald, associate professor and head of the Laboratory of Neural Systems, has received the 2016 W. Alden Spencer Award. The prize, given by Columbia University, recognizes outstanding research contributions in the field of neuroscience. Freiwald shares the award with his long-time colla...

Study uncovers how cells organize the growth of their structural filaments

To take shape, to move and to reproduce, cells need internal scaffolding composed of slender filaments known as microtubules. Before the cell can use microtubules for these and other essential functions, it must first organize them into carefully crafted bundles, which become the basis for three ...

A possible explanation for why male mice tolerate stress better than females

The nerves we feel before a stressful event—like speaking in public, for example—are normally kept in check by a complex system of circuits in our brain. Now, scientists at Rockefeller University have identified a key molecule within this circuitry that is responsible for relieving anxiety. Intr...

Four Rockefeller scientists named 2016 HHMI Faculty Scholars

Four Rockefeller University scientists—Daniel Kronauer, Luciano Marraffini, Agata Smogorzewska, and Sohail Tavazoie—have been named Howard Hughes Medical Institute Faculty Scholars. The Faculty Scholars program, a new collaboration between HHMI, the Simons Foundation, and the Bill & Melinda Gate...

Rockefeller neuroscientist Cori Bargmann to lead science work at Chan Zuckerberg Initiative

Cori Bargmann, an internationally recognized neuroscientist who heads the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior at The Rockefeller University, has been named the incoming president of science at the Chan Zuckerberg Initiative (CZI), the philanthropy funded by Facebook f...

Neuroscientist Cori Bargmann to lead science work at Chan Zuckerberg Initiative

Cori Bargmann, an internationally recognized neuroscientist who heads the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior at Rockefeller, has been named the incoming president of science at the Chan Zuckerberg Initiative (CZI), the philanthropy funded by Facebook founder Mark Zuc...

Four postdocs honored with 2016 Tri-Institutional Breakout Awards

NEW YORK, NY—Four young life scientists from Memorial Sloan Kettering Cancer Center, The Rockefeller University, and Weill Cornell Medicine are the winners of the 2016 Tri-Institutional Breakout Awards for Junior Investigators. The awards, established last year by three winners of the 2013 Breakt...

Structural images shed new light on a cancer-linked potassium channel

    Most cells in the body carry on their surface tiny pores through which potassium ions travel. In controlling the flow of these positively charged ions, the channel helps the cell maintain its electrical balance. One particular type of potassium channel, called Eag1, has been found...

Resistance to antidepressants linked to metabolism

Often, clinical depression has company; it shows up in the brain alongside metabolic abnormalities, such as elevated blood sugar, in the body. While studying an experimental antidepressant in rats, Rockefeller University researchers and their colleagues at Karolinska Institutet in Sweden found so...

New approach exposes 3D structure of Alzheimer’s proteins within the brain

Alzheimer’s disease clouds memory, dims the mind, and distorts behavior. Its ravages also show up within the physical structure of the brain, perhaps most prominently as sticky clumps of a naturally occurring but harmful protein called amyloid-β. A team at The Rockefeller University used a new...

Rockefeller’s newest faculty member studies birdsong to illuminate the origins of human language

by Katherine Fenz, media relations manager The ability to speak has allowed our species to pass knowledge between generations, articulate complex ideas, and build societies. Erich Jarvis, the newest addition to Rockefeller’s faculty, uses songbirds as a model to study the molecular mechan...

Mary E. Hatten and Daniel Kronauer honored with teaching awards

by Alexandra MacWade, assistant editor Mary E. Hatten, Frederick P. Rose Professor and head of the Laboratory of Developmental Neurobiology, and Daniel Kronauer, assistant professor and head of the Laboratory of Social Evolution and Behavior, were honored at this year’s Convocation luncheon w...

Neurobiologist interested in memory to join Rockefeller faculty

For humans, the ability to form and recall memories is what gives meaning to existence. Memory is what allows us to learn, to form relationships, and to feel emotions. Priya Rajasethupathy, the most recent addition to Rockefeller’s faculty, studies the mechanisms that make memories possible, work...

Neurobiologist interested in memory to join Rockefeller faculty

by Wynne Parry, science writer Currently a postdoc at Stanford, Dr. Rajasethupathy will join the university as a tenure-track assistant professor and head of laboratory in May. She is the third new scientist to emerge from Rockefeller’s fall 2015 open recruitment process, making this year...

Do artificial sweeteners live up to the promise of sweetness without harm? An ongoing clinical study investigates

There was a time when Thomas Huber, a molecular biologist at The Rockefeller University, was drinking about 36 ounces of diet cola a day. More than a year ago, Huber, a research assistant professor in Thomas P. Sakmar’s Laboratory of Chemical Biology and Signal Transduction, became curious about ...

New insights into muscular dystrophy point to potential treatment avenues

The average healthy man is 54 percent muscle by mass, but people with muscular dystrophy, an incurable, genetic condition, have almost no muscle at terminal stages of the disease. New research from The Rockefeller University provides insights about what causes patients’ muscles to degenerate and ...

Researchers find new signs of stress damage in the brain, plus hope for prevention

Chronic stress can make us worn-out, anxious, depressed—in fact, it can change the architecture of the brain. New research at The Rockefeller University shows that when mice experience prolonged stress, structural changes occur within a little-studied region of their amygdala, a part of the brain...

New technique captures the activity of an entire brain in a snapshot

When it comes to measuring brain activity, scientists have tools that can take a precise look at a small slice of the brain (less than one cubic millimeter), or a blurred look at a larger area. Now, researchers at The Rockefeller University have described a new technique that combines the best of...

35 labs and counting: How the Robertson Therapeutic Development Fund speeds translational research at Rockefeller

by Alexandra MacWade, assistant editor Developing a new medical product is a complex, high-risk endeavor. Of the thousands of clinically promising concepts scientists formulate each year, only a small fraction move beyond the lab. The Robertson TDF was created to advance work that has gone beyon...

Researchers use new CRISPR-based strategy to replicate disease in cells

To explore in detail how specific genetic errors can lead to disease, scientists need to perform experiments in cells that carry these exact mutations. Now, the ability to create these cellular replicas using new genome editing technology has been facilitated thanks to work by Rockefeller Univers...

Nathaniel Heintz and Stanislas Leibler elected to the National Academy of Sciences

Nathaniel Heintz, James and Marilyn Simons Professor and head of the Laboratory of Molecular Biology, and Stanislas Leibler, Gladys T. Perkin Professor and head of the Laboratory of Living Matter, have been elected to the U.S. National Academy of Sciences. They are among 84 new national and 21 ne...

An experimental Alzheimer’s drug reverses genetic changes thought to spur the disease

Aging takes its toll on the brain, and the cells of the hippocampus—a brain region with circuitry crucial to learning and memory—are particularly vulnerable to changes that can lead to Alzheimer’s disease or cognitive decline. With the hope of counteracting the changes that can lead to these t...

In the News - Stat - Tessier-Lavigne

Scientists solve CRISPR's 'Energizer Bunny' problem   "'It works beautifully,' Tessier-Lavigne said. With standard CRISPR-Cas9, 6 percent to 35 percent of the edits were clean, without random insertions and deletions due to Cas9’s repeated cuts, but with their upgrade, the percentage of clean e...

A common brain cell shapes the nervous system in unexpected ways

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them—similarly to how the plastic casing of an electric cable insulates the copper wire within—allowing electrical and chemical impulses to travel faster. In the past, neuroscientists considered ...

A newly discovered way for cells to die

Some cells are meant to live, and some are meant to die. The linker cell of Caenorhabditis elegans, a tiny worm that is a favored model organism for biologists, is among those destined for termination. This cell helps determine the shape of the gonad in male worms—and then it dies, after two days...

Sweet tooth? Flies have it too—and new research explains how they know what to eat and when to stop

All animals, including humans, love sweet food. But if you’re someone who never turns down dessert under normal circumstances, try wolfing down six donuts as a scientific experiment. Even the moistest, most velvety piece of chocolate cake will seem a lot less appetizing—and you will likely eat l...

In the News - New York Times - Vosshall

Mapping a Genetic Strategy to Fight the Zika Virus "Aware of the new technology, Dr. Vosshall floated the idea of a new Aedes map on Twitter: 'The Aedes aegypti mosquito is infecting millions with #Zika and #Dengue,' she wrote on Jan. 28, 'but we still haven’t put all the pieces of its genome tog...

Using magnetic forces to control neurons, study finds the brain plays key role in glucose metabolism

To learn what different cells do, scientists switch them on and off and observe what the effects are. There are many methods that do this, but they all have problems: too invasive, or too slow, or not precise enough. Now, a new method to control the activity of neurons in mice, devised by scienti...