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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
Displaying 164 of 2761 articles.

New smell test could aid early detection of Alzheimer’s and Parkinson’s

Problems with olfaction have been linked to a variety of health conditions. Scientists have developed new tests to detect smell loss more reliably.

Stress has dramatically different effects on male and female mouse brains

Scientists have found unexpected differences in how male and female mice respond to stress. Their findings are raising big questions about sex discrepancies in the brain and their impact on neuropsychiatric disease.

Rockefeller University biologist Michael W. Young honored with Nobel Prize for pioneering studies on circadian rhythm

Rockefeller University biologist Michael W. Young, who studies the biological clocks that regulate sleep, metabolism, and response to disease, is this year’s recipient of the Nobel Prize in Physiology or Medicine.

How the brain recognizes familiar faces

Scientists have located two areas in the brain that help us recognize familiar faces. The discovery will help them delve deeper into the relationship between face recognition, memory, and social knowledge.

First mutant ants shed light on evolution of social behavior

Scientists disrupted a gene essential for sensing pheromones, resulting in severe deficiencies in the ants’ social behaviors and their ability to survive within a colony.

Hunger-controlling brain cells may offer path for new obesity drugs

Within the oldest part of the brain, scientists have found cells in charge of controlling appetite and eating. The discovery could revitalize efforts to develop drugs for obesity that make us less hungry.

Faster-acting antidepressants may finally be within reach

Neuroscientists have taken a major step toward answering longstanding questions about how Prozac and similar drugs act in the brain. Their findings could lead to better antidepressants that don't take weeks to kick in.

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In brief: How a microRNA protects against liver cancer

New insights about gene regulation in liver cells could lead to better treatments for a common tumor type.

In brief: Mapping the errors that disrupt heartbeat

By determining the structure of a protein linked to a deadly form of arrhythmia, scientists have gained new insights about the condition.

Scientists use algorithm to peer through opaque brains

A new algorithm allows scientists to record the activity of individual neurons within a volume of brain tissue.

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In brief: A closer look at why some drugs cause arrhythmia

Scientists have identified the features that render a potassium channel in the heart vulnerable to interference by a range of drugs.

Researchers create interactive touchscreen for dolphins

To learn more about dolphin cognition and communication, researchers have developed an underwater touchscreen using optical technology, the first of its kind.

Scientists identify a neural circuit that rotates a fly’s internal compass

Researchers have uncovered the neurons that spin a fly’s internal compass when the insect turns—the first such mechanism identified in any animal.

Newly discovered brain network offers clues to social cognition

By studying rhesus monkeys, researchers have identified a brain network dedicated to processing social interactions—a discovery that offers tantalizing clues to the origins of our ability to understand what other people are thinking.

Mary E. Hatten is elected to the National Academy of Sciences

With Hatten’s election, the Rockefeller faculty now has 39 members or foreign associates of the National Academy of Sciences.

Study identifies “night owl” gene variant

Scientists have discovered a common mutation that might explain why some people have trouble going to sleep at night and getting up early. The gene alteration slows the internal biological clock that regulates our sleeping patterns.

Changes in the vascular system may trigger Alzheimer’s disease

In some people whose cognitive functions are weakened due to Alzheimer’s, the disease can be traced back to changes in the brain’s blood vasculature. Scientists have found that a protein involved in blood clotting and inflammation might offer a potential path to new drugs.

For biologists studying tiny worms, new technologies make big improvements

Two new technologies are helping scientists understand new aspects of organ and nervous system development in C. elegans. One allows them to image worms developing in a natural environment, while the other makes it possible to track single neurons as the worms grow.

Study tests the “three-hit” theory of autism

Since the first case was documented in the United States in 1938, the causes of autism have remained elusive. Hundreds of genes, as well as environmental exposures, have been implicated in these brain disorders. Sex also seems to have something to do with it: About 80 percent of children diagnose...

Paul Greengard Professorship established with $5 million gift from the Fisher Center Foundation

Late last year, guests at the President’s House raised a glass in celebration of one of Rockefeller’s most beloved colleagues. In his nearly 35 years at Rockefeller, Paul Greengard has led pioneering studies that have transformed our understanding of how the nervous system works, and have paved ...

New research explains why a common bacterium can produce severe illness

As much as we try to avoid it, ­we are constantly sharing germs with those around us. But even when two people have the same infection, the resulting illnesses can be dramatically different—mild for one person, severe or even life-threatening for the other. Now, new research from The Rockefell...

Talking Science lecture introduces students to the genetic aspects of infectious diseases

As he opened this year’s Talking Science lecture, geneticist Jean-Laurent Casanova made a stark observation to his teenage audience: “If we had been here 150 years ago, about half of you would already have died.” The primary reason, he told the 350 high school students and 60 teachers present,...

Crowdsourcing effort helps researchers predict how a molecule will smell

You can anticipate a color before you see it, based solely on the length of light waves. Music can be interpreted from notes on a page without being heard. Not so with odor.

Mouse studies offer new insights about cocaine’s effect on the brain

 Cocaine is one of the most addictive substances known to man, and for good reason: By acting on levels of the “feel-good” chemical dopamine, it produces a tremendous sensation of euphoria. Now the laboratory of Rockefeller University Professor and Nobel Laureate Paul Greengard has shown...

Newly discovered beetle species named after Rockefeller’s Daniel Kronauer

 Scientists can rack up many awards, but to have one’s name cemented in scientific nomenclature is a special kind of honor. In an homage to his mentor Daniel Kronauer, former Rockefeller postdoctoral associate Christoph von Beeren has named a new species of beetle Nymphister kronaueri. ...

MacKinnon lab charts the anatomy of three molecular channels

Using a state-of-the-art imaging technology in which molecules are deep frozen, scientists in Roderick MacKinnon’s lab at Rockefeller University have reconstructed in unprecedented detail the three-dimensional architecture of three channels that provide a path for specific types of ions to travel...

New research offers clues into how the brain shapes perception to control behavior

What you see is not always what you get. And that, researchers at The Rockefeller University have discovered, is a good thing. “Every time you move your eye, the whole world moves on your retina,” says Gaby Maimon, head of the Laboratory of Integrative Brain Function. “But you don’t perce...

New molecular map reveals how cells spew out potassium

New research from Roderick MacKinnon's Laboratory of Molecular Neurobiology and Biophysics at The Rockefeller University has determined, for the first time, the complete structure of an ion channel that plays an important role in cellular electrical signaling by sending potassium ions out of the ...

Fifty years after landmark methadone discovery, stigmas and misunderstandings persist

Methadone, the first pharmacological treatment for heroin addiction, was pioneered 50 years ago by Rockefeller University’s Mary Jeanne Kreek and her colleagues. Since then the drug, which is widely used in treatment programs across the globe, has saved countless lives and allowed millions of her...

Jean-Laurent Casanova receives the 2016 Inserm Grand Prix

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, has won the 2016 Inserm Grand Prix for his work on the genetic basis of infectious diseases. The prestigious award, given annually by Inserm—the French National Institute of Health and ...