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New research shows that mosquitoes sense repellent through their legs

Scientists made the surprising discovery that the insects’ displeasure for touching DEET, the active ingredient in many repellents, helps prevent bites.
Bacteriophages inject their DNA into bacteria, typically resulting in the bacterium’s demise. CRISPR-Cas systems defend bacteria against these attacks.
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To curb infection, bacteria direct their defenses against themselves

To fight off invading viruses, bacteria have evolved a slew of creative defense tactics. New research shows that in some cases, microbes go to great lengths to keep an infection from spreading, even destroying bits of their own genetic material.
Here, a winner (red) engulfs a loser (green)
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Cellular rivalry promotes healthy skin development

Scientists have discovered a curious phenomenon taking place in mouse skin: cells compete with one another for the chance to develop into mature tissue. The findings indicate that this antagonism is key to creating healthy skin.
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Researchers find genetic link to tuberculosis

Rockefeller scientists have identified a genetic condition that makes people prone to developing tuberculosis. In a British population, they found that the condition underlies one percent of cases of the disease—a finding that may ultimately lead to new treatment options.
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Study explores genetic differences among people’s gut microbes, and their health consequences

Scientists have found that small genetic differences can cause the same gut microbe to behave differently in different people, and affect the overall health of their human hosts.
Human astrocytes
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Research on repetitive worm behavior may have implications for understanding human disease

Studying microscopic worms, Rockefeller scientists have identified a brain circuit that drives repetitive behavior—providing potential clues for understanding some human psychiatric conditions.
Tumor stem cells
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Study pinpoints what causes relapse after cancer immunotherapy

In many cancer patients who have been treated with immunotherapy, the tumor comes back. New research identifies the cells responsible for thwarting the treatment and offers new insights into how they do it.
DIPG cells, pictured here, are generally resilient and replicate rapidly. With a dose of MI-2, however, the cells abruptly die.
Science News

New hope for treating a childhood brain cancer

Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.
Activation of hD2R neurons
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Scientists find brain mechanism that naturally combats overeating

Studying a brain region involved in memory, researchers discovered a set of neurons that help mice control their appetite.
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Researchers discover a common link among diverse cancer types

Some cancers have been traced to changes in histones, proteins responsible for packaging DNA and regulating genes. Now, research from Rockefeller scientists shows that, among tumors, mutations to these proteins are a lot more common than previously suspected.
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